| UniProt/SwissProt ID: | KAT5_HUMAN |
| Description: | K(lysine) acetyltransferase 5 [Source:HGNC Symbol;Acc:5275] |
| Location: | chr11 q13.1 |
| Node attribute: | substrate; acetylation(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S86 | NGLPGsRPGSP | PhosphoSitePlus; phosphoELM | |
| S90 | GSRPGsPEREV | PhosphoSitePlus; phosphoELM | |
| S202 | EDSQDsSDGIP | PhosphoSitePlus | |
| Y472 | YYKGQyILTLS | MOZ_SAS | PhosphoSitePlus |
| S190 | GRKRKsNCLGT | PhosphoSitePlus | |
| T281 | LQRHLtKCDLR | PhosphoSitePlus | |
| S119 | NGLPGsRPGSP | CDK1 | HPRD |
| T227 | HDDIVtRMKNI | PhosphoSitePlus | |
| T158 | VVSPAtPVPSE | PhosphoSitePlus | |
| S90 | GSRPGsPEREV | CCNB1 | HPRD |
| S90 | GSRPGsPEREV | CDK1 | HPRD; phosphoELM |
| S123 | GSRPGsPEREV | CDK1 | HPRD |
| S86 | NGLPGsRPGSP | CCNB1 | HPRD |
| S431 | LMGLKsESGER | MOZ_SAS | PhosphoSitePlus |
| S155 | KVEVVsPATPV | PhosphoSitePlus | |
| S119 | NGLPGsRPGSP | CCNB1 | HPRD |
| S123 | GSRPGsPEREV | CCNB1 | HPRD |
| S86 | NGLPGsRPGSP | CDK1 | HPRD |
| S199 | GTDEDsQDSSD | PhosphoSitePlus | |
| T195 | SNCLGtDEDSQ | PhosphoSitePlus | |
| Dephosphorylation site |
| KAT5_HUMAN do not have dephosphorylation site. |
| Mutation site |
| KAT5_HUMAN do not have mutation site. |
| Differential expressed protein |
| KAT5_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KAT5_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK08_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK3_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK1_HUMAN | KAT5_HUMAN | kinase -> substrate | RegPhos |
| ZAGL2_HUMAN | KAT5_HUMAN | kinase -> substrate | RegPhos |
| CCNB1_HUMAN | KAT5_HUMAN | kinase -> substrate | HPRD |
| BTK_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK6_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KS6A2_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KAT5_HUMAN | ANDR_HUMAN | acetylation | NetPath |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05166 | HTLV-I infection |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0032703 | negative regulation of interleukin-2 production | IDA | biological_process |
| GO:0040008 | regulation of growth | IEA | biological_process |
| GO:0000785 | chromatin | IEA | cellular_component |
| GO:0045892 | negative regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
| GO:0006978 | DNA damage response, signal transduction by p53 cl | IDA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0004402 | histone acetyltransferase activity | IDA | molecular_function |
| GO:0016573 | histone acetylation | IEA | biological_process |
| GO:0030521 | androgen receptor signaling pathway | NAS | biological_process |
| GO:0005730 | nucleolus | IDA | cellular_component |
| GO:0043234 | protein complex | IEA | cellular_component |
| GO:0003713 | transcription coactivator activity | IDA | molecular_function |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0000122 | negative regulation of transcription from RNA poly | IMP | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0032777 | Piccolo NuA4 histone acetyltransferase complex | IDA | cellular_component |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0070491 | repressing transcription factor binding | IPI | molecular_function |
| GO:0005829 | cytosol | IEA | cellular_component |
| GO:0048471 | perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0019048 | virus-host interaction | IEA | biological_process |
| GO:0005667 | transcription factor complex | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0050681 | androgen receptor binding | NAS | molecular_function |
| GO:0006302 | double-strand break repair | IMP | biological_process |
| GO:0032403 | protein complex binding | IEA | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0008134 | transcription factor binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0035267 | NuA4 histone acetyltransferase complex | IDA | cellular_component |
| GO:0016747 | transferase activity, transferring acyl groups oth | IEA | molecular_function |