Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ST38L_HUMAN
Description:serine/threonine kinase 38 like [Source:HGNC Symbol;Acc:17848]
Location:chr12 p11.23
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S265FQNMNsKRKAEPkinasePhosphoSitePlus
T283QLAYStVGTPDPkinasePhosphoSitePlus
S282RQLAYsTVGTPHPRD
S282RQLAYsTVGTPautocatalysisRegPhos
T442VFLNYtYKRFERegPhos
Y443FLNYTyKRFEGPkinase_CPhosphoSitePlus
T236DFGLCtGLKKAPkinasePhosphoSitePlus
T450RFEGLtQRGSIPhosphoSitePlus; HPRD; RegPhos
T442VFLNYtYKRFEMST3phosphoELM
S454LTQRGsIPTYMHPRD
T75HARKEtEFLRLPhosphoSitePlus; RegPhos
Y289VGTPDyIAPEVPkinasePhosphoSitePlus
S282RQLAYsTVGTPNDR2phosphoELM; RegPhos
T442VFLNYtYKRFEPkinase_CPhosphoSitePlus
S282RQLAYsTVGTPPkinasePhosphoSitePlus
S282RQLAYsTVGTPMST3RegPhos

Dephosphorylation site
ST38L_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000373684L359ITCGAOvarian Cancer21720365, 18772890
ENSP00000373684V104LTCGAOvarian Cancer21720365, 18772890
ENSP00000373684G99AGreenman2007Neoplasms by Histologic Type17344846, 18428421
ENSP00000373684G99AGreenman2007Other Cancer(all cancer)17344846, 18428421

Differential expressed protein
ST38L_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ST38L_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK24_HUMANST38L_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
ST38L_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
ST38L_HUMANKPCD_HUMANkinase -> substrateRobert H Newman (2013)
ST38L_HUMANSRC8_HUMANkinase -> substrateRobert H Newman (2013)
ST38L_HUMANIF4B_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANST38L_HUMANkinase -> substrateRegPhos
ST38L_HUMANST38L_HUMANkinase -> substrateRegPhos
ST38L_HUMANFGR_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ST38L_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004674protein serine/threonine kinase activityIDAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0003779actin bindingIEAmolecular_function
GO:0051128regulation of cellular component organizationIEAbiological_process
GO:0006468protein phosphorylationIDAbiological_process
GO:0000287magnesium ion bindingIDAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005886plasma membraneIDAcellular_component
GO:0015629actin cytoskeletonIEAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0007243intracellular protein kinase cascadeIDAbiological_process
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0005737cytoplasmIEAcellular_component


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