| UniProt/SwissProt ID: | ST38L_HUMAN |
| Description: | serine/threonine kinase 38 like [Source:HGNC Symbol;Acc:17848] |
| Location: | chr12 p11.23 |
| Node attribute: | kinase; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S265 | FQNMNsKRKAE | Pkinase | PhosphoSitePlus |
| T283 | QLAYStVGTPD | Pkinase | PhosphoSitePlus |
| S282 | RQLAYsTVGTP | HPRD | |
| S282 | RQLAYsTVGTP | autocatalysis | RegPhos |
| T442 | VFLNYtYKRFE | RegPhos | |
| Y443 | FLNYTyKRFEG | Pkinase_C | PhosphoSitePlus |
| T236 | DFGLCtGLKKA | Pkinase | PhosphoSitePlus |
| T450 | RFEGLtQRGSI | PhosphoSitePlus; HPRD; RegPhos | |
| T442 | VFLNYtYKRFE | MST3 | phosphoELM |
| S454 | LTQRGsIPTYM | HPRD | |
| T75 | HARKEtEFLRL | PhosphoSitePlus; RegPhos | |
| Y289 | VGTPDyIAPEV | Pkinase | PhosphoSitePlus |
| S282 | RQLAYsTVGTP | NDR2 | phosphoELM; RegPhos |
| T442 | VFLNYtYKRFE | Pkinase_C | PhosphoSitePlus |
| S282 | RQLAYsTVGTP | Pkinase | PhosphoSitePlus |
| S282 | RQLAYsTVGTP | MST3 | RegPhos |
| Dephosphorylation site |
| ST38L_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000373684 | L359I | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000373684 | V104L | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000373684 | G99A | Greenman2007 | Neoplasms by Histologic Type | 17344846, 18428421 | ENSP00000373684 | G99A | Greenman2007 | Other Cancer(all cancer) | 17344846, 18428421 |
| Differential expressed protein |
| ST38L_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ST38L_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| STK24_HUMAN | ST38L_HUMAN | kinase -> substrate | RegPhos; Robert H Newman (2013) |
| ST38L_HUMAN | MLX_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ST38L_HUMAN | KPCD_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ST38L_HUMAN | SRC8_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ST38L_HUMAN | IF4B_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ZAGL2_HUMAN | ST38L_HUMAN | kinase -> substrate | RegPhos |
| ST38L_HUMAN | ST38L_HUMAN | kinase -> substrate | RegPhos |
| ST38L_HUMAN | FGR_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ST38L_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004674 | protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0003779 | actin binding | IEA | molecular_function |
| GO:0051128 | regulation of cellular component organization | IEA | biological_process |
| GO:0006468 | protein phosphorylation | IDA | biological_process |
| GO:0000287 | magnesium ion binding | IDA | molecular_function |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0015629 | actin cytoskeleton | IEA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0007243 | intracellular protein kinase cascade | IDA | biological_process |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0005737 | cytoplasm | IEA | cellular_component |