Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RUVB2_HUMAN
Description:RuvB-like 2 (E. coli) [Source:HGNC Symbol;Acc:10475]
Location:chr19 q13.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S26RIGAHsHIRGLPhosphoSitePlus
S220YDAMGsQTKFVphosphoELM
T81AGQPGtGKTAIPhosphoSitePlus
S110GSEIFsLEMSKPhosphoSitePlus
Y172EMETIyDLGTKTIP49PhosphoSitePlus
S220YDAMGsQTKFVTIP49PhosphoSitePlus
Y215TRARDyDAMGSTIP49PhosphoSitePlus
T419RKRKGtEVQVDTIP49PhosphoSitePlus
T222AMGSQtKFVQCTIP49PhosphoSitePlus
S431IKRVYsLFLDETIP49PhosphoSitePlus
Y430DIKRVySLFLDTIP49PhosphoSitePlus

Dephosphorylation site
RUVB2_HUMAN do not have dephosphorylation site.

Mutation site
RUVB2_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000221413colorectal cancerNormal vs. CancertissueUp1.619098285

Hyperphosphorylation site
RUVB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ST17A_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
DYRK4_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
MP2K7_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
FAK2_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
DYRK2_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
KS6A2_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
MAPK5_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
M4K2_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
MK08_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
CDK4_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
FGFR2_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
ANPRB_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
KSYK_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
KS6A4_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
TGFR2_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
PIM1_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
PKN1_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
CLK2_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
STK16_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
PTK6_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
KPCZ_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
FRK_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
TNI3K_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
KKCC1_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
M3K7_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)
TBK1_HUMANRUVB2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
RUVB2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016363nuclear matrixIEAcellular_component
GO:0043967histone H4 acetylationIDAbiological_process
GO:0035267NuA4 histone acetyltransferase complexIDAcellular_component
GO:0016887ATPase activityIDAmolecular_function
GO:0071339MLL1 complexIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0051082unfolded protein bindingTASmolecular_function
GO:0003678DNA helicase activityIDAmolecular_function
GO:0004003ATP-dependent DNA helicase activityTASmolecular_function
GO:0034644cellular response to UVIMPbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0006281DNA repairIEAbiological_process
GO:0005622intracellularIDAcellular_component
GO:0006457protein foldingTASbiological_process
GO:0040008regulation of growthIEAbiological_process
GO:0042802identical protein bindingIDAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0006310DNA recombinationIEAbiological_process
GO:0003684damaged DNA bindingIEAmolecular_function
GO:0031011Ino80 complexIDAcellular_component
GO:0043968histone H2A acetylationIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016020membraneIEAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0006260DNA replicationIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0032508DNA duplex unwindingIDAbiological_process


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