Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KCC2G_HUMAN
Description:calcium/calmodulin-dependent protein kinase II gamma [Source:HGNC Symbol;Acc:1463]
Location:chr10 q22.2
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S338SNNKNsLVSPAHPRD
S235AYDFPsPEWDTPkinase_CAMKPhosphoSitePlus
T343SLEPQtTVVHNHPRD
T380GIKGStESCNTHPRD
T348GIKGStESCNTHPRD
T287MHRQEtVECLRPhosphoSitePlus; HPRD; phosphoELM
S346LLNKKsDGGVKHPRD
T350VVHNAtDGIKGHPRD
S311TTMLVsRNFSVHPRD
S325SSAPAsPAASAHPRD
Y14RFTDDyQLFEEPkinase_CAMKPhosphoSitePlus
S419MQPQPsLCSSAPhosphoSitePlus
S350KGSTEsCNTTTHPRD
S311TTMLVsRNFSAPhosphoSitePlus; HPRD
S319FSAAKsLLNKKPhosphoSitePlus; HPRD; phosphoELM
S315VSRNFsAAKSLPhosphoSitePlus; HPRD; phosphoELM
Y231IKAGAyDFPSPPkinase_CAMKPhosphoSitePlus
T341VVHNAtDGIKGHPRD
S359KGSTEsCNTTTHPRD
S382KGSTEsCNTTTHPRD
S320SVGRQsSAPASHPRD
S338SNNKNsLEPQTHPRD
S276WVCQRsTVASMPhosphoSitePlus; HPRD
T371GIKGStESCNTHPRD
S341KNSLVsPAQEPHPRD
T344LEPQTtVVHNAHPRD
S373KGSTEsCNTTTHPRD
S349SNNKNsLVSPAPhosphoSitePlus
S352KNSLVsPAQEPPhosphoSitePlus
S114SEADAsHCIHQPkinase_CAMKPhosphoSitePlus
T306KGAILtTMLVSPhosphoSitePlus; HPRD
S356DGIKGsTESCNHPRD
T357GIKGStESCNTHPRD
S280RSTVAsMMHRQPhosphoSitePlus
S379DGIKGsTESCNHPRD
S370DGIKGsTESCNHPRD
S325LLNKKsDGGVKPhosphoSitePlus; HPRD
S315VSRNFsVGRQSHPRD
T373VVHNAtDGIKGHPRD
T364VVHNAtDGIKGHPRD
S333GVKPQsNNKNSHPRD
S384KGSTEsCNTTTPhosphoSitePlus
S347DGIKGsTESCNHPRD

Dephosphorylation site
KCC2G_HUMAN do not have dephosphorylation site.

Mutation site
KCC2G_HUMAN do not have mutation site.

Differential expressed protein
KCC2G_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KCC2G_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC2G_HUMANKKCC1_HUMANkinase -> substrateRobert H Newman (2013)
KCC2G_HUMANKPCA_HUMANkinase -> substrateRobert H Newman (2013)
KCC2G_HUMANRAD_HUMANkinase -> substrateHPRD
ZAGL2_HUMANKCC2G_HUMANkinase -> substrateRegPhos
KCC2G_HUMANCREM_HUMANkinase -> substrateHPRD
KCC2G_HUMANGRIA4_HUMANkinase -> substrateHPRD
KCC2G_HUMANRYR1_HUMANkinase -> substrateHPRD
KCC2G_HUMANSPRE_HUMANkinase -> substrateHPRD
KCC2G_HUMANGRIA1_HUMANkinase -> substrateHPRD
KCC2G_HUMANFLNA_HUMANkinase -> substrateHPRD
KCC2G_HUMANTY3H_HUMANkinase -> substrateHPRD
KCC2G_HUMANSYN1_HUMANkinase -> substrateHPRD
KCC2G_HUMANETS1_HUMANkinase -> substrateRobert H Newman (2013)
KCC2G_HUMANSTAT1_HUMANkinase -> substrateHPRD
KCC2G_HUMANPEA15_HUMANkinase -> substrateHPRD
KCC2G_HUMANUHMK1_HUMANkinase -> substrateRobert H Newman (2013)
KCC2G_HUMANADCY3_HUMANkinase -> substrateHPRD
KCC2G_HUMANMYLK_HUMANkinase -> substrateHPRD
KCC2G_HUMANEGFR_HUMANkinase -> substrateHPRD
KCC2G_HUMANPLCB3_HUMANkinase -> substrateHPRD
KCC2G_HUMANATF1_HUMANkinase -> substrateHPRD
KCC2G_HUMANCLAT_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04722Neurotrophin signaling pathway
hsa04720Long-term potentiation
hsa04310Wnt signaling pathway
hsa04725Cholinergic synapse
hsa05152Tuberculosis
hsa04916Melanogenesis
hsa05214Glioma
hsa04971Gastric acid secretion
hsa04912GnRH signaling pathway
hsa04740Olfactory transduction
hsa04114Oocyte meiosis
hsa05031Amphetamine addiction
hsa04728Dopaminergic synapse
hsa04012ErbB signaling pathway
hsa04020Calcium signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030666endocytic vesicle membraneTAScellular_component
GO:0005516calmodulin bindingNASmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0051924regulation of calcium ion transportTASbiological_process
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0006468protein phosphorylationNASbiological_process
GO:0005524ATP bindingNASmolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0006816calcium ion transportIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0004683calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0033017sarcoplasmic reticulum membraneIEAcellular_component
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0007399nervous system developmentIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0030154cell differentiationIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0060333interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0000082G1/S transition of mitotic cell cycleIEAbiological_process
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0004723calcium-dependent protein serine/threonine phosphaNASmolecular_function
GO:0030073insulin secretionNASbiological_process
GO:0046777protein autophosphorylationIEAbiological_process
GO:0005954calcium- and calmodulin-dependent protein kinase cTAScellular_component
GO:0014733regulation of skeletal muscle adaptationTASbiological_process
GO:0007268synaptic transmissionTASbiological_process


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