Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RAD_HUMAN
Description:Ras-related associated with diabetes [Source:HGNC Symbol;Acc:10446]
Location:chr16 q22.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S214RSREVsVDEGRRasPhosphoSitePlus
S257RLRRDsKEANAPRKCAHPRD
S257RLRRDsKEANAPKCaRegPhos
S257RLRRDsKEANAPKCbRegPhos
S273TRRREsLGKKACAMK2GHPRD
S299AFRAKsKSCHDPKCbRegPhos
S299AFRAKsKSCHDPKCaRegPhos
S290IVARNsRKMAFCSNK2A1HPRD
S299AFRAKsKSCHDPRKCBHPRD
S299AFRAKsKSCHDPRKCAHPRD
S257RLRRDsKEANAPhosphoSitePlus
S214RSREVsVDEGRCK2a1RegPhos
S290IVARNsRKMAFPKCbRegPhos
S290IVARNsRKMAFPKCaRegPhos
S290IVARNsRKMAFPRKCBHPRD
S290IVARNsRKMAFPRKCAHPRD
S273TRRREsLGKKAPRKACAHPRD
S257RLRRDsKEANAPRKACAHPRD
S290IVARNsRKMAFCK2a1RegPhos
S257RLRRDsKEANAPRKCBHPRD
S273TRRREsLGKKACK2a1-rsRegPhos
S257RLRRDsKEANACSNK2A1HPRD
S257RLRRDsKEANAPKACaRegPhos
S290IVARNsRKMAFCK2a1-rsRegPhos
S290IVARNsRKMAFPhosphoSitePlus
S214RSREVsVDEGRCK2_groupphosphoELM; RegPhos
S273TRRREsLGKKACK2a1RegPhos
S273TRRREsLGKKACaMK2gRegPhos
S79EDSEDsLSSGGPhosphoSitePlus
S257RLRRDsKEANACK2a1-rsRegPhos
S214RSREVsVDEGRCK2a1-rsRegPhos
S273TRRREsLGKKACSNK2A1HPRD
S214RSREVsVDEGRCSNK2A1HPRD
S273TRRREsLGKKAPKACaRegPhos
S299AFRAKsKSCHDPhosphoSitePlus
S273TRRREsLGKKAPhosphoSitePlus
S39PLHRRsMPVDEPhosphoSitePlus
S214RSREVsVDEGRPKCaRegPhos
S214RSREVsVDEGRPKCbRegPhos
S301RAKSKsCHDLSPhosphoSitePlus
S214RSREVsVDEGRPRKCBHPRD
S214RSREVsVDEGRPRKCAHPRD
S257RLRRDsKEANACK2a1RegPhos

Dephosphorylation site
RAD_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000388744*309YCOSMICIntestines Cancer17932254
ENSP00000299759*309YCOSMICIntestines Cancer17932254

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000388744Breast CancerNormal vs. CancertissueUp18257521

Hyperphosphorylation site
RAD_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC2G_HUMANRAD_HUMANkinase -> substrateHPRD
KPCA_HUMANRAD_HUMANkinase -> substrateHPRD
CSK21_HUMANRAD_HUMANkinase -> substrateHPRD
KPCB_HUMANRAD_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
RAD_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003924GTPase activityIEAmolecular_function
GO:0007264small GTPase mediated signal transductionIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0005525GTP bindingIEAmolecular_function
GO:0007165signal transductionIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005516calmodulin bindingIEAmolecular_function
GO:0006184GTP catabolic processIEAbiological_process
GO:0015031protein transportIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005622intracellularIEAcellular_component


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