Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SYN1_HUMAN
Description:synapsin I [Source:HGNC Symbol;Acc:11494]
Location:chrX p11.23
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y301ALTKTyATAEPSynapsin_CPhosphoSitePlus
S39PPGAHsPGATPPhosphoSitePlus; phosphoELM; RegPhos
S9LRRRLsDSNFMPKACaRegPhos
S605PTRQAsQAGPVCAMK2GHPRD
S553PPASPsPQRQAPhosphoSitePlus; phosphoELM; RegPhos
S568ATRQTsVSGPACAMK2GHPRD
S9LRRRLsDSNFMPRKACAHPRD
S9LRRRLsDSNFMPAK2HPRD; RegPhos
S568ATRQTsVSGPACaMK2gRegPhos
S665LNKSQsLTNAFRegPhos
S438HGQTPsPGALPKISphosphoELM; RegPhos
S9LRRRLsDSNFMPhosphoSitePlus
S11RRLSDsNFMANPhosphoSitePlus
S438HGQTPsPGALPPhosphoSitePlus
S9LRRRLsDSNFMPKA_groupRegPhos
S551ARPPAsPSPQRCDK_groupphosphoELM; RegPhos
S432SPGRGsHGQTPPhosphoSitePlus
S520PQQPAsQAAPPRegPhos
S605PTRQAsQAGPVCaMK2_groupRegPhos
Y312FIDAKyDVRVQRegPhos
S449LGRQTsQQPAGPhosphoSitePlus
S67SPAAPsPGSSGCDK5HPRD; RegPhos
S9LRRRLsDSNFMCaMK1aRegPhos
S9LRRRLsDSNFMCAMK1HPRD
S704FASLFsDRegPhos
S605PTRQAsQAGPVPhosphoSitePlus; phosphoELM
T436GSHGQtPSPGAPhosphoSitePlus
S67SPAAPsPGSSGPhosphoSitePlus; RegPhos
T567QATRQtSVSGPPhosphoSitePlus
S605PTRQAsQAGPVPAK1HPRD; RegPhos
T448PLGRQtSQQPAPhosphoSitePlus
S62VAPAAsPAAPSCDK5HPRD; RegPhos
S332MRTSVsGNWKTSynapsin_CPhosphoSitePlus
T337SGNWKtNTGSARegPhos
T512RLPSPtSAPQQRegPhos
S605PTRQAsQAGPVCaMK2gRegPhos
S62VAPAAsPAAPSRegPhos
S568ATRQTsVSGPACaMK2_groupRegPhos
S605PTRQAsQAGPVPAK_groupphosphoELM; RegPhos
S510PQRLPsPTSAPHPRD; RegPhos
S553PPASPsPQRQACDK5HPRD; RegPhos
S605PTRQAsQAGPVPAK3HPRD; RegPhos
S551ARPPAsPSPQRCDK5HPRD; RegPhos
S551ARPPAsPSPQRPhosphoSitePlus; phosphoELM; RegPhos
S427RQRDAsPGRGSPhosphoSitePlus; phosphoELM; RegPhos

Dephosphorylation site
SYN1_HUMAN do not have dephosphorylation site.

Mutation site
SYN1_HUMAN do not have mutation site.

Differential expressed protein
SYN1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SYN1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC1A_HUMANSYN1_HUMANkinase -> substrateHPRD
PKN1_HUMANSYN1_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANSYN1_HUMANkinase -> substrateRegPhos
KCC2G_HUMANSYN1_HUMANkinase -> substrateHPRD
KPCA_HUMANSYN1_HUMANkinase -> substrateHPRD
CDK5_HUMANSYN1_HUMANkinase -> substrateRegPhos
UHMK1_HUMANSYN1_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
PAK3_HUMANSYN1_HUMANkinase -> substrateHPRD; RegPhos
PAK2_HUMANSYN1_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
SYN1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007269neurotransmitter secretionIEAbiological_process
GO:0005794Golgi apparatusIEAcellular_component
GO:0003779actin bindingIEAmolecular_function
GO:0005215transporter activityTASmolecular_function
GO:0000795synaptonemal complexIEAcellular_component
GO:0007268synaptic transmissionTASbiological_process
GO:0008021synaptic vesicleIEAcellular_component
GO:0043229intracellular organelleIEAcellular_component
GO:0045202synapseIEAcellular_component
GO:0048786presynaptic active zoneIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0030054cell junctionIEAcellular_component
GO:0005829cytosolIEAcellular_component
GO:0030425dendriteIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0003824catalytic activityIEAmolecular_function
GO:0030672synaptic vesicle membraneIEAcellular_component


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