Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PI4KA_HUMAN
Description:phosphatidylinositol 4-kinase, catalytic, alpha [Source:HGNC Symbol;Acc:8983]
Location:chr22 q11.21
Node attribute:Enzyme(target); Enzyme(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S199KRKTSsVSSISPhosphoSitePlus; phosphoELM
S849MRVLRsTDPDRPhosphoSitePlus
T472HSQYHtVAGNDPhosphoSitePlus
S188NQDTRsNLDITHPRD
Y973HKDQPyYDIPDPhosphoSitePlus
S448HSVTPsLRDFLPhosphoSitePlus
T446VVHSVtPSLRDPhosphoSitePlus
Y2032NRSRTyDMIQYPhosphoSitePlus
T192VCQEGtLKRKTPhosphoSitePlus
S207SISQVsPERGMPhosphoSitePlus; phosphoELM
S172GVRRRsFNDFRPhosphoSitePlus
Y861QVMFCyFEDKAPhosphoSitePlus
S444PVVVHsVTPSLPhosphoSitePlus
Y1731VLDIDyKSGTPPhosphoSitePlus
S468LYKYHsQYHTVPhosphoSitePlus
S178FNDFRsILPSNPhosphoSitePlus
S202TSSVSsISQVSPhosphoSitePlus; phosphoELM
S204SVSSIsQVSPEPhosphoSitePlus; phosphoELM
S1378NQDTRsNLDITPhosphoSitePlus
T636VVYSAtKDYKDPhosphoSitePlus
S182RSILPsNLLTVPhosphoSitePlus
T197TLKRKtSSVSSPhosphoSitePlus
S198LKRKTsSVSSIPhosphoSitePlus; phosphoELM
T850RVLRStDPDRFPhosphoSitePlus
S705LKASSsAGNLGPhosphoSitePlus
Y1826LFVFPyRVVATPI3_PI4_kinasePhosphoSitePlus
Y633ASSVVySATKDPhosphoSitePlus
S580RCRSDsEDECSHPRD
Y1745AAKAPyLAKFKPhosphoSitePlus
T490EHSEStLNVMSPhosphoSitePlus
Y466VKLYKyHSQYHPhosphoSitePlus
Y789RSVLQyNSAMKPhosphoSitePlus
Y974KDQPYyDIPDAPhosphoSitePlus
S201KTSSVsSISQVPhosphoSitePlus
Y470KYHSQyHTVAGPhosphoSitePlus
Y1096YAGEVyGMIRFPhosphoSitePlus
T2031SNRSRtYDMIQPhosphoSitePlus
Y843VYRLEyMRVLRPhosphoSitePlus
S140AFGRYsNMEESPhosphoSitePlus
S2029FLSNRsRTYDMPhosphoSitePlus
Y139RAFGRySNMEEPhosphoSitePlus

Dephosphorylation site
PI4KA_HUMAN do not have dephosphorylation site.

Mutation site
PI4KA_HUMAN do not have mutation site.

Differential expressed protein
PI4KA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PI4KA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PI4KA_HUMANPLCD3_HUMANenzyme catalysisKEGG
PI4KA_HUMANI5P2_HUMANenzyme catalysisKEGG
PLCD3_HUMANPI4KA_HUMANenzyme catalysisKEGG
PI51C_HUMANPI4KA_HUMANenzyme catalysisKEGG
FYV1_HUMANPI4KA_HUMANenzyme catalysisKEGG
CDIPT_HUMANPI4KA_HUMANenzyme catalysisKEGG
PI4KA_HUMANMTM1_HUMANenzyme catalysisKEGG
PTEN_HUMANPI4KA_HUMANenzyme catalysisKEGG
PI4KA_HUMANPI3R5_HUMANenzyme catalysisKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04070Phosphatidylinositol signaling system
hsa01100Metabolic pathways
hsa00562Inositol phosphate metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0044281small molecule metabolic processTASbiological_process
GO:0006661phosphatidylinositol biosynthetic processTASbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0016773phosphotransferase activity, alcohol group as acceIEAmolecular_function
GO:0005829cytosolTAScellular_component
GO:00044301-phosphatidylinositol 4-kinase activityIEAmolecular_function
GO:0048015phosphatidylinositol-mediated signalingIEAbiological_process
GO:0006644phospholipid metabolic processTASbiological_process
GO:0007268synaptic transmissionTASbiological_process
GO:0005798Golgi-associated vesicleTAScellular_component
GO:0005488bindingIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0007165signal transductionNASbiological_process


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