Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IMPA1_HUMAN
Description:inositol(myo)-1(or 4)-monophosphatase 1 [Source:HGNC Symbol;Acc:6050]
Location:chr8 q21.13
Node attribute:Enzyme(source); Enzyme(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T168LGSSRtPETVRInositol_PPhosphoSitePlus
S38VMLKSsPVDLVInositol_PPhosphoSitePlus
S56EKMLIsSIKEKInositol_PPhosphoSitePlus
S37NVMLKsSPVDLHPRD; phosphoELM
T44PVDLVtATDQKInositol_PPhosphoSitePlus
T161KSLLVtELGSSInositol_PPhosphoSitePlus

Dephosphorylation site
IMPA1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000256108G164SCOSMICMelanoma

Differential expressed protein
IMPA1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IMPA1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
IMPA1_HUMANIMPA1_HUMANenzyme catalysisKEGG
IMPA1_HUMANINP4A_HUMANenzyme catalysisKEGG
CDIPT_HUMANIMPA1_HUMANenzyme catalysisKEGG
IMPA1_HUMANINPP_HUMANenzyme catalysisKEGG
PLCD3_HUMANIMPA1_HUMANenzyme catalysisKEGG
MTM1_HUMANIMPA1_HUMANenzyme catalysisKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04070Phosphatidylinositol signaling system
hsa00562Inositol phosphate metabolism
hsa01100Metabolic pathways

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIDAcellular_component
GO:0046855inositol phosphate dephosphorylationIDAbiological_process
GO:0046854phosphatidylinositol phosphorylationIEAbiological_process
GO:0006796phosphate-containing compound metabolic processIMPbiological_process
GO:0007165signal transductionIMPbiological_process
GO:0042803protein homodimerization activityIPImolecular_function
GO:0005739mitochondrionIDAcellular_component
GO:0052832inositol monophosphate 3-phosphatase activityIEAmolecular_function
GO:0052833inositol monophosphate 4-phosphatase activityIEAmolecular_function
GO:0008934inositol monophosphate 1-phosphatase activityIMPmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0006661phosphatidylinositol biosynthetic processIMPbiological_process
GO:0006021inositol biosynthetic processIEAbiological_process


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