| UniProt/SwissProt ID: | CDIPT_HUMAN |
| Description: | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:1769] |
| Location: | chr16 p11.2 |
| Node attribute: | Enzyme(target); Enzyme(source) |
| Phosphorylation site |
| CDIPT_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| CDIPT_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000457339 | *214C | COSMIC | Neoplasms by Histologic Type | 12673678 | ENSP00000219789 | *214Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000457339 | *214Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000454453 | *214Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000454453 | *214C | COSMIC | Neoplasms by Histologic Type | 12673678 | ENSP00000219789 | *214C | COSMIC | Neoplasms by Histologic Type | 12673678 |
| Differential expressed protein |
| CDIPT_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CDIPT_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDIPT_HUMAN | MTM1_HUMAN | enzyme catalysis | KEGG |
| PTEN_HUMAN | CDIPT_HUMAN | enzyme catalysis | KEGG |
| CDIPT_HUMAN | IMPA1_HUMAN | enzyme catalysis | KEGG |
| CDIPT_HUMAN | FYV1_HUMAN | enzyme catalysis | KEGG |
| CDIPT_HUMAN | PI3R5_HUMAN | enzyme catalysis | KEGG |
| CDIPT_HUMAN | PI4KA_HUMAN | enzyme catalysis | KEGG |
| PLCD3_HUMAN | CDIPT_HUMAN | enzyme catalysis | KEGG |
| CDIPT_HUMAN | CHK2_HUMAN | enzyme catalysis | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa01100 | Metabolic pathways |
| hsa00564 | Glycerophospholipid metabolism |
| hsa04070 | Phosphatidylinositol signaling system |
| hsa00562 | Inositol phosphate metabolism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0006661 | phosphatidylinositol biosynthetic process | IDA | biological_process |
| GO:0043178 | alcohol binding | IEA | molecular_function |
| GO:0008654 | phospholipid biosynthetic process | IEA | biological_process |
| GO:0046341 | CDP-diacylglycerol metabolic process | IEA | biological_process |
| GO:0016780 | phosphotransferase activity, for other substituted | IEA | molecular_function |
| GO:0006661 | phosphatidylinositol biosynthetic process | IEA | biological_process |
| GO:0005789 | endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransfer | IDA | molecular_function |
| GO:0030246 | carbohydrate binding | IEA | molecular_function |
| GO:0019992 | diacylglycerol binding | IEA | molecular_function |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransfer | IEA | molecular_function |
| GO:0030145 | manganese ion binding | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0006644 | phospholipid metabolic process | TAS | biological_process |
| GO:0046474 | glycerophospholipid biosynthetic process | TAS | biological_process |