| UniProt/SwissProt ID: | STK24_HUMAN |
| Description: | serine/threonine kinase 24 [Source:HGNC Symbol;Acc:11403] |
| Location: | chr13 q32.2 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S305 | HDDSSsEDSDA | HPRD | |
| T178 | QIKRNtFVGTP | HPRD | |
| T18 | NKRRAtLPHPG | PKA_group | phosphoELM |
| S317 | HDDSSsEDSDA | PhosphoSitePlus; HPRD | |
| S299 | WKAEQsHDDSS | HPRD | |
| Y303 | ELIDRyKRWKA | PhosphoSitePlus | |
| T194 | NTFVGtPFWMA | Pkinase | PhosphoSitePlus |
| T184 | GQLTDtQIKRN | HPRD; SysPTM | |
| S320 | SSSEDsDAETD | HPRD | |
| S434 | RLQRYsLSGGG | DUF1241 | PhosphoSitePlus |
| T184 | GQLTDtQIKRN | Pkinase | PhosphoSitePlus; SysPTM |
| T190 | QIKRNtFVGTP | HPRD | |
| S311 | WKAEQsHDDSS | HPRD | |
| S4 | VQSG | HPRD | |
| S315 | QSHDDsSSEDS | PhosphoSitePlus; HPRD | |
| T182 | VAGQLtDTQIK | Pkinase | PhosphoSitePlus |
| S304 | SHDDSsSEDSD | HPRD | |
| T18 | NKRRAtLPHPG | PhosphoSitePlus; HPRD | |
| S316 | SHDDSsSEDSD | PhosphoSitePlus; HPRD | |
| T324 | DSDAEtDGQAS | HPRD | |
| Y93 | QCDSPyVTKYY | Pkinase | PhosphoSitePlus |
| T190 | QIKRNtFVGTP | Pkinase | PhosphoSitePlus |
| T194 | NTFVGtPFWMA | HPRD; phosphoELM | |
| S8 | HSPVQsGLPGM | HPRD | |
| T182 | NTFVGtPFWMA | HPRD | |
| T312 | DSDAEtDGQAS | HPRD | |
| S308 | SSSEDsDAETD | HPRD | |
| S303 | QSHDDsSSEDS | HPRD | |
| T172 | GQLTDtQIKRN | HPRD | |
| Dephosphorylation site |
| STK24_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000365730 | F372L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000380651 | F360L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000365730 | A414V | BIOMART | Lung Cancer | 21930507, 21930502 | ENSP00000365730 | A414V | Ding2008 | Lung Cancer | 18948947 |
| Differential expressed protein |
| STK24_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| STK24_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| STK24_HUMAN | ST38L_HUMAN | kinase -> substrate | RegPhos; Robert H Newman (2013) |
| STK24_HUMAN | TSN_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | NEK6_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | KAT5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | ASAP3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | IF4H_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | CSDE1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | MDFI_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | SRC8_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | ENC2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | BPL1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | TFAM_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | TDRD1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | HNRH3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK24_HUMAN | JAK2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| STK24_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016301 | kinase activity | IEA | molecular_function |
| GO:0006921 | cellular component disassembly involved in executi | TAS | biological_process |
| GO:0006915 | apoptotic process | TAS | biological_process |
| GO:0048679 | regulation of axon regeneration | IMP | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0004672 | protein kinase activity | TAS | molecular_function |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0030336 | negative regulation of cell migration | IMP | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0008631 | intrinsic apoptotic signaling pathway in response | IMP | biological_process |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0046777 | protein autophosphorylation | IDA | biological_process |
| GO:0006468 | protein phosphorylation | IDA | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0006917 | induction of apoptosis | IMP | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |