Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CEBPB_HUMAN
Description:CCAAT/enhancer binding protein (C/EBP), beta [Source:HGNC Symbol;Acc:1834]
Location:chr20 q13.13
Node attribute:substrate; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S325LSRELsTLRNLCaMK2aRegPhos
T235SSPPGtPSPADMAPK3phosphoELM
T266SKAKKtVDKHSRSK3RegPhos
S76RAIDFsPYLEPPhosphoSitePlus
S231TSSSSsPPGTPPhosphoSitePlus; HPRD; RegPhos
S141EYGYVsLGRLGPhosphoSitePlus
S325LSRELsTLRNLCaMK2_groupRegPhos
S325LSRELsTLRNLCaM-KII_groupphosphoELM
S325LSRELsTLRNLI_LWEQ; Nup54; DivIC; HALPhosphoSitePlus
T235SSPPGtPSPADErk1(MAPK3RegPhos
T266SKAKKtVDKHSRPS6KA1HPRD
T235SSPPGtPSPADPhosphoSitePlus; phosphoELM
T235SSPPGtPSPADMAPK_groupphosphoELM; RegPhos
S288IAVRKsRDKAKI_LWEQ; Nup54; bZIP_2PhosphoSitePlus
Y137KKPAEyGYVSLPhosphoSitePlus
T266SKAKKtVDKHSRSK1RegPhos
T266SKAKKtVDKHSRSK-1phosphoELM
S288IAVRKsRDKAKHPRD; RegPhos
S223SGSSGsLSTSSPhosphoSitePlus
Y78IDFSPyLEPLGPhosphoSitePlus
S288IAVRKsRDKAKPKA_groupphosphoELM; RegPhos
S325LSRELsTLRNLCAMK2AHPRD
T235SSPPGtPSPADMAPK1HPRD
Y139PAEYGyVSLGRPhosphoSitePlus
T266SKAKKtVDKHSI_LWEQ; Nup54PhosphoSitePlus
T235SSPPGtPSPADErk2RegPhos

Dephosphorylation site
CEBPB_HUMAN do not have dephosphorylation site.

Mutation site
CEBPB_HUMAN do not have mutation site.

Differential expressed protein
CEBPB_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CEBPB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC2A_HUMANCEBPB_HUMANkinase -> substrateHPRD
MK03_HUMANCEBPB_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANCEBPB_HUMANkinase -> substrateRegPhos
MK01_HUMANCEBPB_HUMANkinase -> substrateHPRD
KS6A1_HUMANCEBPB_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)
KCC4_HUMANCEBPB_HUMANkinase -> substrateRobert H Newman (2013)
KS6A2_HUMANCEBPB_HUMANkinase -> substrateRegPhos
CEBPB_HUMANSFTPD_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANCDN1A_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANSAA2_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANCRP_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANCCL5_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANB2LA1_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANIL6_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANTOP1_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANTSG6_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANICAM1_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANISK1_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANCP19A_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANI18BP_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANMDR1_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANMEFV_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANIL1B_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANIL10_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05152Tuberculosis
hsa05202Transcriptional misregulation in cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003705RNA polymerase II distal enhancer sequence-specifiIEAmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0045444fat cell differentiationIEAbiological_process
GO:0034976response to endoplasmic reticulum stressIDAbiological_process
GO:0071230cellular response to amino acid stimulusIEAbiological_process
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0045408regulation of interleukin-6 biosynthetic processIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0001892embryonic placenta developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0001077RNA polymerase II core promoter proximal region seIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0006953acute-phase responseTASbiological_process
GO:0035259glucocorticoid receptor bindingIEAmolecular_function
GO:0006954inflammatory responseTASbiological_process
GO:0045669positive regulation of osteoblast differentiationIEAbiological_process
GO:0030182neuron differentiationIEAbiological_process
GO:0060644mammary gland epithelial cell differentiationIEAbiological_process
GO:0003705RNA polymerase II distal enhancer sequence-specifiISSmolecular_function
GO:0006917induction of apoptosisIEAbiological_process
GO:0006955immune responseTASbiological_process
GO:0050873brown fat cell differentiationIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0006355regulation of transcription, DNA-dependentIDAbiological_process
GO:0008134transcription factor bindingIEAmolecular_function
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0016363nuclear matrixIEAcellular_component
GO:0000790nuclear chromatinIEAcellular_component
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0033598mammary gland epithelial cell proliferationIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorNASmolecular_function
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0005737cytoplasmIEAcellular_component