| UniProt/SwissProt ID: | CP19A_HUMAN |
| Description: | cytochrome P450, family 19, subfamily A, polypeptide 1 [Source:HGNC Symbol;Acc:2594] |
| Location: | chr15 q21.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y441 | GCAGKyIAMVM | p450 | PhosphoSitePlus |
| T484 | LHPDEtKNMLE | p450 | PhosphoSitePlus |
| T392 | PVKKGtNIILN | HPRD | |
| T201 | LDTSNtLFLRI | p450 | PhosphoSitePlus |
| Y241 | KISWLyKKYEK | p450 | PhosphoSitePlus |
| Y112 | MKHNHySSRFG | p450 | PhosphoSitePlus |
| Y361 | MENFIyESMRY | p450 | PhosphoSitePlus |
| Y220 | VKIQGyFDAWQ | HPRD | |
| S497 | FTPRNsDRCLE | PhosphoSitePlus | |
| T162 | LVRMVtVCAES | p450 | PhosphoSitePlus; SysPTM |
| T392 | PVKKGtNIILN | p450 | PhosphoSitePlus |
| T162 | LVRMVtVCAES | HPRD; phosphoELM; SysPTM | |
| Dephosphorylation site |
| CP19A_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000379683 | E269K | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000379683 | P8S | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| CP19A_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CP19A_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CEBPB_HUMAN | CP19A_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| CP19A_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005506 | iron ion binding | IEA | molecular_function |
| GO:0016712 | oxidoreductase activity, acting on paired donors, | IEA | molecular_function |
| GO:0005783 | endoplasmic reticulum | IDA | cellular_component |
| GO:0006703 | estrogen biosynthetic process | TAS | biological_process |
| GO:0060736 | prostate gland growth | IEA | biological_process |
| GO:0006805 | xenobiotic metabolic process | TAS | biological_process |
| GO:0070330 | aromatase activity | IDA | molecular_function |
| GO:0008202 | steroid metabolic process | TAS | biological_process |
| GO:0005789 | endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0016705 | oxidoreductase activity, acting on paired donors, | IEA | molecular_function |
| GO:0008209 | androgen metabolic process | IEA | biological_process |
| GO:0006694 | steroid biosynthetic process | TAS | biological_process |
| GO:0009055 | electron carrier activity | IEA | molecular_function |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0055114 | oxidation-reduction process | IEA | biological_process |
| GO:0019825 | oxygen binding | TAS | molecular_function |
| GO:0020037 | heme binding | IEA | molecular_function |
| GO:0016020 | membrane | TAS | cellular_component |