Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IL10_HUMAN
Description:interleukin 10 [Source:HGNC Symbol;Acc:5962]
Location:chr1 q32.1
Node attribute:gene

Phosphorylation site
IL10_HUMAN do not have phosphorylation site.

Dephosphorylation site
IL10_HUMAN do not have dephosphorylation site.

Mutation site
IL10_HUMAN do not have mutation site.

Differential expressed protein
IL10_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IL10_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SP1_HUMANIL10_HUMANTF -> target geneTRANSFAC
STAT3_HUMANIL10_HUMANTF -> target geneTRANSFAC
CEBPA_HUMANIL10_HUMANTF -> target geneTRANSFAC
CEBPB_HUMANIL10_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
IL10_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030595leukocyte chemotaxisTASbiological_process
GO:0045348positive regulation of MHC class II biosynthetic pIEAbiological_process
GO:0005125cytokine activityNASmolecular_function
GO:0030183B cell differentiationNASbiological_process
GO:0051091positive regulation of sequence-specific DNA bindiIDAbiological_process
GO:0032689negative regulation of interferon-gamma productionIEAbiological_process
GO:0008083growth factor activityNASmolecular_function
GO:0007267cell-cell signalingICbiological_process
GO:0050715positive regulation of cytokine secretionIDAbiological_process
GO:0042742defense response to bacteriumIEAbiological_process
GO:0071222cellular response to lipopolysaccharideNASbiological_process
GO:0002740negative regulation of cytokine secretion involvedIDAbiological_process
GO:0051930regulation of sensory perception of painIEAbiological_process
GO:0044130negative regulation of growth of symbiont in hostIEAbiological_process
GO:0005125cytokine activityIEAmolecular_function
GO:0005141interleukin-10 receptor bindingNASmolecular_function
GO:0032695negative regulation of interleukin-12 productionIEAbiological_process
GO:0060670branching involved in labyrinthine layer morphogenIEAbiological_process
GO:0045347negative regulation of MHC class II biosynthetic pTASbiological_process
GO:0002904positive regulation of B cell apoptotic processIDAbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0043066negative regulation of apoptotic processNASbiological_process
GO:0006955immune responseIEAbiological_process
GO:0030886negative regulation of myeloid dendritic cell actiIEAbiological_process
GO:0001818negative regulation of cytokine productionIEAbiological_process
GO:0010468regulation of gene expressionIDAbiological_process
GO:0045019negative regulation of nitric oxide biosynthetic pIEAbiological_process
GO:0032720negative regulation of tumor necrosis factor produIEAbiological_process
GO:0042100B cell proliferationNASbiological_process
GO:0034465response to carbon monoxideIEAbiological_process
GO:0005141interleukin-10 receptor bindingIEAmolecular_function
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0051045negative regulation of membrane protein ectodomainIDAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0007253cytoplasmic sequestering of NF-kappaBNASbiological_process
GO:0045355negative regulation of interferon-alpha biosynthetNASbiological_process
GO:0042092type 2 immune responseTASbiological_process
GO:0010033response to organic substanceIEAbiological_process
GO:0030889negative regulation of B cell proliferationIDAbiological_process
GO:0042536negative regulation of tumor necrosis factor biosyIEAbiological_process
GO:0045191regulation of isotype switchingNASbiological_process
GO:0042130negative regulation of T cell proliferationNASbiological_process
GO:0014823response to activityIEAbiological_process
GO:0032868response to insulin stimulusIEAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0032715negative regulation of interleukin-6 productionIDAbiological_process
GO:0071392cellular response to estradiol stimulusIEAbiological_process
GO:0051384response to glucocorticoid stimulusIDAbiological_process
GO:0014854response to inactivityIEAbiological_process
GO:0050728negative regulation of inflammatory responseIEAbiological_process
GO:0002875negative regulation of chronic inflammatory responIEAbiological_process
GO:0032800receptor biosynthetic processIDAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0030097hemopoiesisTASbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0006954inflammatory responseIDAbiological_process
GO:0002237response to molecule of bacterial originIDAbiological_process