Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TESK2_HUMAN
Description:testis-specific kinase 2 [Source:HGNC Symbol;Acc:11732]
Location:chr1 p34.1
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S456IRRWRsLPGSPPhosphoSitePlus
S477VGREEsLSDGPPhosphoSitePlus
S346VKRLSsLDDKIPhosphoSitePlus
S460RSLPGsPEFLHPhosphoSitePlus
S367IWLSRsQSDIFPhosphoSitePlus
S488PPRLSsLKYRVPhosphoSitePlus
S369LSRSQsDIFSRPhosphoSitePlus

Dephosphorylation site
TESK2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000343940S33NBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000361158S241CBIOMARTBreast Cancer21930507, 21930502
ENSP00000343940S241CBIOMARTBreast Cancer21930507, 21930502
ENSP00000361156S241CBIOMARTBreast Cancer21930507, 21930502
ENSP00000361156S33NBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000361158S33NBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000361158G11AHPIbreast ductal carcinoma17344846

Differential expressed protein
TESK2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TESK2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TESK2_HUMANTIF1A_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANCOF1_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)
TESK2_HUMANPOLK_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANRUVB1_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANOTU7B_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANKPCA_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANCHK1_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANZN626_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANZYX_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANKS6A2_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANPINX1_HUMANkinase -> substrateRobert H Newman (2013)
TESK2_HUMANDEST_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
TESK2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006468protein phosphorylationIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0030036actin cytoskeleton organizationIEAbiological_process
GO:0048041focal adhesion assemblyIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0005634nucleusISScellular_component
GO:0004674protein serine/threonine kinase activityISSmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0007283spermatogenesisISSbiological_process
GO:0007283spermatogenesisIEAbiological_process
GO:0004712protein serine/threonine/tyrosine kinase activityIEAmolecular_function
GO:0004672protein kinase activityTASmolecular_function
GO:0006468protein phosphorylationISSbiological_process
GO:0048041focal adhesion assemblyISSbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0030036actin cytoskeleton organizationISSbiological_process


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