Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KCC1D_HUMAN
Description:calcium/calmodulin-dependent protein kinase ID [Source:HGNC Symbol;Acc:19341]
Location:chr10 p13
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T180GDVMStACGTPphosphoELM; SysPTM
T180GDVMStACGTPPkinase_CAMKPhosphoSitePlus; SysPTM
T180GDVMStACGTPCaM-KK_alphaphosphoELM; SysPTM
T180GDVMStACGTPCaMKK1RegPhos; SysPTM
T180GDVMStACGTPCaMKK2RegPhos; SysPTM
S122TEKDAsTLIRQPkinase_CAMKPhosphoSitePlus; SysPTM
Y152PENLLyYSQDEPkinase_CAMKPhosphoSitePlus
S338ASVSSsLSLASPhosphoSitePlus
S8RENGEsSSSWKPhosphoSitePlus
T180GDVMStACGTPCAMKK1HPRD; SysPTM
S122TEKDAsTLIRQHPRD; phosphoELM; SysPTM
S327LHLGSsLDSSNPhosphoSitePlus
T180GDVMStACGTPautocatalysisRegPhos; SysPTM
Y153ENLLYySQDEEPkinase_CAMKPhosphoSitePlus
S326KLHLGsSLDSSPhosphoSitePlus
S179KGDVMsTACGTPkinase_CAMKPhosphoSitePlus

Dephosphorylation site
KCC1D_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000368122T269MTCGAOvarian Cancer21720365, 18772890
ENSP00000368124V363FBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
KCC1D_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KCC1D_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC1D_HUMANNDF1_HUMANkinase -> substrateRobert H Newman (2013)
KCC1D_HUMANSMAD3_HUMANkinase -> substrateRobert H Newman (2013)
KCC1D_HUMANASAP3_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANKCC1D_HUMANkinase -> substrateRobert H Newman (2013)
KCC1D_HUMANPHB2_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANKCC1D_HUMANkinase -> substrateRobert H Newman (2013)
KKCC1_HUMANKCC1D_HUMANkinase -> substrateHPRD
KCC1D_HUMANDAZP1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KCC1D_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005954calcium- and calmodulin-dependent protein kinase cTAScellular_component
GO:0006468protein phosphorylationIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0042981regulation of apoptotic processIEAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0090023positive regulation of neutrophil chemotaxisIEAbiological_process
GO:0060267positive regulation of respiratory burstIMPbiological_process
GO:0010976positive regulation of neuron projection developmeIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0090023positive regulation of neutrophil chemotaxisISSbiological_process
GO:0071622regulation of granulocyte chemotaxisIMPbiological_process
GO:0050766positive regulation of phagocytosisIMPbiological_process
GO:0032793positive regulation of CREB transcription factor aIDAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0010976positive regulation of neuron projection developmeISSbiological_process
GO:0005516calmodulin bindingIEAmolecular_function
GO:0050773regulation of dendrite developmentIMPbiological_process
GO:0004683calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function


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