Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ANS1A_HUMAN
Description:ankyrin repeat and sterile alpha motif domain containing 1A [Source:HGNC Symbol;Acc:20961]
Location:chr6 p21.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S480DHRRSsSSRSQPhosphoSitePlus
S692ERQKIsGLRTLPhosphoSitePlus
T696ISGLRtLEQSVPhosphoSitePlus
S677EKIMSsIGEGIPhosphoSitePlus; HPRD
S331ISSMDsISQKSPhosphoSitePlus
T958KDLRGtESTQDHPRD
S336SISQKsQGDVEPhosphoSitePlus
S647GSRSEsLSNCSPhosphoSitePlus; HPRD; phosphoELM
Y454EEDEHpYELLLHPRD
S481HRRSSsSRSQDPhosphoSitePlus
Y568SKRVGyLTGLPPhosphoSitePlus
S479KDHRRsSSSRSPhosphoSitePlus
S628LSKSDsDLLTCPhosphoSitePlus; HPRD
Y834LADRPyEEPPQPhosphoSitePlus; HPRD
S482RRSSSsRSQDSPhosphoSitePlus
S887RRRHDsLHDPAPhosphoSitePlus
Y427HIDKKyFPLTAPhosphoSitePlus
S666SPSFAsEWDEIPhosphoSitePlus
S333SMDSIsQKSQGPhosphoSitePlus
T460YELLLtAETKKPhosphoSitePlus; HPRD
S620AELKLsRSLSKPhosphoSitePlus
Y455EDEHPyELLLTPhosphoSitePlus; HPRD
S652SLSNCsIGKKRPhosphoSitePlus; HPRD
S845KPPRFsQLRCQPhosphoSitePlus
S445PRIHGsAAREEPhosphoSitePlus
S663LEKSPsFASEWPhosphoSitePlus; HPRD; phosphoELM
S949ANYLGsMLIKDHPRD
Y946GYEANyLGSMLHPRD
S854CQDLLsQTSSPPhosphoSitePlus
T463LLTAEtKKVVLHPRD
S661KRLEKsPSFASPhosphoSitePlus; HPRD
S645TMGSRsESLSNPhosphoSitePlus
S828KRIIAsLADRPSAM_1PhosphoSitePlus
S622LKLSRsLSKSDPhosphoSitePlus; HPRD
S626RSLSKsDSDLLHPRD
Y922SLAAPyAPVQSPhosphoSitePlus
T610SRAPPtSKPKAPhosphoSitePlus
T318KEVDKtPPPQPPhosphoSitePlus; HPRD

Dephosphorylation site
ANS1A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000353518S66NCOSMICSkin Cancer21984974
ENSP00000353518Q264HCOSMICOvarian Cancer21720365
ENSP00000353518R606*TCGAOvarian Cancer21720365, 18772890
ENSP00000353518Q264HTCGAOvarian Cancer21720365, 18772890
ENSP00000353518R606*COSMICOvarian Cancer21720365
ENSP00000353518L168ICOSMICHead and Neck Cancer21798897

Differential expressed protein
ANS1A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ANS1A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
HIPK4_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
GRK5_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
TGFR2_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
EPHA3_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
CLK1_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
DYRK4_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
PI3R4_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
PK3C3_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
CLK3_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
BMPR2_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
PAK4_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
KPCZ_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
GSK3A_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
FGFR1_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
WNK1_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ANS1A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006929substrate-dependent cell migrationIEAbiological_process
GO:0048013ephrin receptor signaling pathwayISSbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0016322neuron remodelingIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0016322neuron remodelingISSbiological_process
GO:0006929substrate-dependent cell migrationISSbiological_process
GO:0046875ephrin receptor bindingIEAmolecular_function
GO:0048013ephrin receptor signaling pathwayIEAbiological_process
GO:0043005neuron projectionISScellular_component
GO:0043005neuron projectionIEAcellular_component


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