Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CLK3_HUMAN
Description:CDC-like kinase 3 [Source:HGNC Symbol;Acc:2071]
Location:chr15 q24.1
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S197PRRSRsRSHDRPkinasePhosphoSitePlus
S281SSKRSsRSVEDPkinasePhosphoSitePlus
S265KRRTRsCSSASPkinasePhosphoSitePlus
S133SSKRSsRSVEDHPRD
Y166DPYLSyRWKRRPkinasePhosphoSitePlus
S78EERSPsFGEDYHPRD
S175RRRSYsREHEGPkinasePhosphoSitePlus
S157CKRYRsPEPDPPkinasePhosphoSitePlus
S226EERSPsFGEDYPkinasePhosphoSitePlus
S224RCEERsPSFGEphosphoELM
S165PDPYLsYRWKRPkinasePhosphoSitePlus
S135KRSSRsVEDDKHPRD
S283KRSSRsVEDDKPkinasePhosphoSitePlus
S25WKRRRsYSREHHPRD
S199RSRSRsHDRLPPkinasePhosphoSitePlus
S271CSSASsRSQQSPkinasePhosphoSitePlus
Y26KRRRSySREHEHPRD
T314NLGEGtFGKVVPkinasePhosphoSitePlus
S157CKRYRsPEPDPphosphoELM
Y218RDSDTyRCEERPkinasePhosphoSitePlus
S67RERRDsDTYRCHPRD
S76RCEERsPSFGEHPRD
S9CKRYRsPEPDPHPRD
Y218RDSDTyRCEERphosphoELM
S132QSSKRsSRSVEHPRD
T217RRDSDtYRCEEphosphoELM
S215RERRDsDTYRCphosphoELM
Y155HHCKRyRSPEPPhosphoSitePlus; phosphoELM
S226EERSPsFGEDYphosphoELM
S224RCEERsPSFGEPkinasePhosphoSitePlus
S49PRRSRsRSHDRHPRD
S215RERRDsDTYRCPkinasePhosphoSitePlus
S199RSRSRsHDRLPphosphoELM
S51RSRSRsHDRLPHPRD
Y163PEPDPyLSYRWPkinasePhosphoSitePlus
S280QSSKRsSRSVEPkinasePhosphoSitePlus
S270SCSSAsSRSQQPkinasePhosphoSitePlus
Y7SPEPHPRD
T69RRDSDtYRCEEHPRD
S27RRRSYsREHEGHPRD
Y70RDSDTyRCEERHPRD
T217RRDSDtYRCEEPkinasePhosphoSitePlus

Dephosphorylation site
CLK3_HUMAN do not have dephosphorylation site.

Mutation site
CLK3_HUMAN do not have mutation site.

Differential expressed protein
CLK3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CLK3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLK3_HUMANXRCC5_HUMANkinase -> substrateRobert H Newman (2013)
CLK3_HUMANBPL1_HUMANkinase -> substrateRobert H Newman (2013)
CLK3_HUMANIASPP_HUMANkinase -> substrateRobert H Newman (2013)
CLK3_HUMANANS1A_HUMANkinase -> substrateRobert H Newman (2013)
CLK3_HUMAN2A5D_HUMANkinase -> substrateRobert H Newman (2013)
MK01_HUMANCLK3_HUMANkinase -> substrateRobert H Newman (2013)
CLK3_HUMANSRSF1_HUMANkinase -> substrateRobert H Newman (2013)
CLK3_HUMANKPCD_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CLK3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0045111intermediate filament cytoskeletonIDAcellular_component
GO:0001669acrosomal vesicleIEAcellular_component
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0004672protein kinase activityIEAmolecular_function
GO:0016301kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0046777protein autophosphorylationIEAbiological_process
GO:0043484regulation of RNA splicingIDAbiological_process
GO:0004712protein serine/threonine/tyrosine kinase activityIEAmolecular_function
GO:0018108peptidyl-tyrosine phosphorylationIEAbiological_process
GO:0006468protein phosphorylationIDAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0016607nuclear speckIEAcellular_component


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