Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NAR4_HUMAN
Description:ADP-ribosyltransferase 4 (Dombrock blood group) [Source:HGNC Symbol;Acc:726]
Location:chr12 p12.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T21TVPPAtMRIWLPhosphoSitePlus
T16ILLPTtVPPATPhosphoSitePlus

Dephosphorylation site
NAR4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000228936G264ECOSMICSkin Cancer21984974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000228936Breast CancerNormal vs. Cancercell lineUp1.820052998
ENSP00000228936Breast CancerNormal vs. Cancercell lineUp1.920052998
ENSP00000228936Breast CancerMetastasiscell lineUp1.120052998

Hyperphosphorylation site
NAR4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
LCK_HUMANNAR4_HUMANkinase -> substrateHPRD; RegPhos
LYN_HUMANNAR4_HUMANkinase -> substrateNetPath
ZAGL2_HUMANNAR4_HUMANkinase -> substrateRegPhos
TEC_HUMANNAR4_HUMANkinase -> substrateNetPath
FAK2_HUMANNAR4_HUMANkinase -> substrateRobert H Newman (2013)
TBK1_HUMANNAR4_HUMANkinase -> substrateRobert H Newman (2013)
TYK2_HUMANNAR4_HUMANkinase -> substrateRobert H Newman (2013)
IKKB_HUMANNAR4_HUMANkinase -> substrateNetPath
M4K5_HUMANNAR4_HUMANkinase -> substrateRobert H Newman (2013)
RET_HUMANNAR4_HUMANkinase -> substrateHPRD; RegPhos
INSR_HUMANNAR4_HUMANkinase -> substrateRegPhos
KS6B1_HUMANNAR4_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
NAR4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031225anchored to membraneIEAcellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0003956NAD(P)+-protein-arginine ADP-ribosyltransferase acNASmolecular_function
GO:0016020membraneNAScellular_component
GO:0006525arginine metabolic processNASbiological_process
GO:0006471protein ADP-ribosylationNASbiological_process


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