Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KCC1A_HUMAN
Description:calcium/calmodulin-dependent protein kinase I [Source:HGNC Symbol;Acc:1459]
Location:chr3 p25.3
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T177GSVLStACGTPCaMK1aRegPhos
T177GSVLStACGTPCaM-KI_groupphosphoELM
T177GSVLStACGTPCaM-KI_alphaphosphoELM
T177GSVLStACGTPCAMKK2HPRD
Y20DIRDIyDFRDVPkinase_CAMKPhosphoSitePlus
T177GSVLStACGTPCaMK1_groupRegPhos
T177GSVLStACGTPCaMKK1RegPhos
T177GSVLStACGTPCaMKK2RegPhos
Y235ILKAEyEFDSPPkinase_CAMKPhosphoSitePlus
Y131LDAVKyLHDLGPkinase_CAMKPhosphoSitePlus
T177GSVLStACGTPPkinase_CAMKPhosphoSitePlus
T177GSVLStACGTPCCDPKRegPhos
T177GSVLStACGTPCAMK1HPRD
S176PGSVLsTACGTPkinase_CAMKPhosphoSitePlus

Dephosphorylation site
KCC1A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000256460P217SGreenman2007Skin Cancer17344846, 18428421

Differential expressed protein
KCC1A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KCC1A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC1A_HUMANIF4G3_HUMANkinase -> substrateHPRD
KKCC2_HUMANKCC1A_HUMANkinase -> substrateHPRD
KCC1A_HUMANNOS1_HUMANkinase -> substrateHPRD
KCC1A_HUMANSYN1_HUMANkinase -> substrateHPRD
KCC4_HUMANKCC1A_HUMANkinase -> substrateRobert H Newman (2013)
KCC1A_HUMANKCC1A_HUMANkinase -> substrateHPRD
KCC1A_HUMANHDAC5_HUMANkinase -> substrateHPRD
KCC1A_HUMANATF1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KCC1A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043393regulation of protein bindingIDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0051835positive regulation of synapse structural plasticiIMPbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0007165signal transductionIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0051147regulation of muscle cell differentiationIDAbiological_process
GO:0005516calmodulin bindingIEAmolecular_function
GO:0006468protein phosphorylationIDAbiological_process
GO:0004683calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0046827positive regulation of protein export from nucleusIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0051149positive regulation of muscle cell differentiationIMPbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0032880regulation of protein localizationIDAbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0006913nucleocytoplasmic transportIEAbiological_process
GO:0007049cell cycleIEAbiological_process
GO:0010976positive regulation of neuron projection developmeIDAbiological_process
GO:0071902positive regulation of protein serine/threonine kiIDAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0004683calmodulin-dependent protein kinase activityISSmolecular_function
GO:0060999positive regulation of dendritic spine developmentIMPbiological_process


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