| UniProt/SwissProt ID: | 2AAB_HUMAN |
| Description: | protein phosphatase 2, regulatory subunit A, beta [Source:HGNC Symbol;Acc:9303] |
| Location: | chr11 q23.1 |
| Node attribute: | substrate; phosphotase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T49 | IKKLStIALAL | HPRD | |
| T59 | LGVERtRSELL | HPRD | |
| S212 | VLELDsVKSEI | PhosphoSitePlus; HPRD | |
| T493 | EWAQNtIVPKV | PhosphoSitePlus | |
| S48 | SIKKLsTIALA | HPRD | |
| Y341 | NQILPyIKELV | PhosphoSitePlus | |
| Dephosphorylation site |
| 2AAB_HUMAN do not have dephosphorylation site. |
| Mutation site |
| 2AAB_HUMAN do not have mutation site. |
| Differential expressed protein |
| 2AAB_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| 2AAB_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| AAPK1_HUMAN | 2AAB_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| TOPK_HUMAN | 2AAB_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK5_HUMAN | 2AAB_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| TRIB3_HUMAN | 2AAB_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK7_HUMAN | 2AAB_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NUAK1_HUMAN | 2AAB_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MYLK2_HUMAN | 2AAB_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| 2AAB_HUMAN | RALA_HUMAN | phosphatase -> substrate | HPRD |
| 2AAB_HUMAN | TF65_HUMAN | phosphatase -> substrate | NetPath |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04728 | Dopaminergic synapse |
| hsa04730 | Long-term depression |
| hsa04530 | Tight junction |
| hsa04350 | TGF-beta signaling pathway |
| hsa05160 | Hepatitis C |
| hsa04114 | Oocyte meiosis |
| hsa05142 | Chagas disease (American trypanosomiasis) |
| hsa04310 | Wnt signaling pathway |
| hsa03015 | mRNA surveillance pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005488 | binding | IEA | molecular_function |
| GO:2001241 | positive regulation of extrinsic apoptotic signali | IMP | biological_process |