Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RALA_HUMAN
Description:v-ral simian leukemia viral oncogene homolog A (ras related) [Source:HGNC Symbol;Acc:9839]
Location:chr7 p14.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y82AIRDNyFRSGERasPhosphoSitePlus
S183RKMEDsKEKNGPhosphoSitePlus; HPRD
S22VIMVGsGGVGKRasPhosphoSitePlus
Y75AGQEDyAAIRDRasPhosphoSitePlus
Y153QWNVNyVETSARasPhosphoSitePlus
Y43EFVEDyEPTKARasPhosphoSitePlus
Y51TKADSyRKKVVRasPhosphoSitePlus
S194KKKRKsLAKRIPhosphoSitePlus
S11PKGQNsLALHKHPRD

Dephosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S183RARKMEDsKEKNGKKPPP2R1BHPRD
S194NGKKKRKsLAKRIREPPP2R1BHPRD

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000005257L14FBIOMARTBreast Cancer21930507, 21930502
ENSP00000005257G59WDing2008, COSMICLung Cancer18948947
ENSP00000005257R176*COSMICSkin Cancer21984974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000005257Breast CancerCancer vs. Cancer (Non-TNBC vs. TNBC)cell lineUp20596302

Hyperphosphorylation site
RALA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
2AAB_HUMANRALA_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05200Pathways in cancer
hsa05212Pancreatic cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030496midbodyIEAcellular_component
GO:0032154cleavage furrowIDAcellular_component
GO:0006913nucleocytoplasmic transportIEAbiological_process
GO:0006184GTP catabolic processIEAbiological_process
GO:0031532actin cytoskeleton reorganizationIDAbiological_process
GO:0006886intracellular protein transportIEAbiological_process
GO:0006887exocytosisIEAbiological_process
GO:0006935chemotaxisTASbiological_process
GO:0007265Ras protein signal transductionTASbiological_process
GO:0030139endocytic vesicleIDAcellular_component
GO:0007049cell cycleIEAbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0005886plasma membraneIDAcellular_component
GO:0007264small GTPase mediated signal transductionIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0015031protein transportIEAbiological_process
GO:0000910cytokinesisIDAbiological_process
GO:0017157regulation of exocytosisIEAbiological_process
GO:0009986cell surfaceIDAcellular_component
GO:0051665membrane raft localizationIEAbiological_process
GO:0051491positive regulation of filopodium assemblyIDAbiological_process
GO:0007165signal transductionTASbiological_process
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0005622intracellularIEAcellular_component
GO:0031755Edg-2 lysophosphatidic acid receptor bindingIDAmolecular_function
GO:0003924GTPase activityIEAmolecular_function
GO:0019048virus-host interactionIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0016020membraneIEAcellular_component


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