Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TBG1_HUMAN
Description:tubulin, gamma 1 [Source:HGNC Symbol;Acc:12417]
Location:chr17 q21.2
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S129READGsDSLEGTubulinPhosphoSitePlus
T307NVMVStGRDRQTubulin_CPhosphoSitePlus
S131ADGSDsLEGFVTubulinPhosphoSitePlus
S284DQSVAsVRKTTHPRD
S364ALSRKsPYLPSTubulin_CPhosphoSitePlus
S32AEHGIsPEGIVTubulinPhosphoSitePlus
S284DQSVAsVRKTTTubulin_CPhosphoSitePlus
S80HSILNsPYAKLTubulinPhosphoSitePlus

Dephosphorylation site
TBG1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000251413R124LCOSMICOvarian Cancer21720365
ENSP00000251413R124LTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000251413Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
TBG1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GNAI2_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAI1_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG12_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG5_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAO_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG11_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAS1_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG10_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAS2_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBB5_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG13_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBB3_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG8_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG2_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG1_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBB1_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBG3_HUMANTBG1_HUMANGprotein -> effectorgpDB
GBB2_HUMANTBG1_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
TBG1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005881cytoplasmic microtubuleIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005814centrioleIEAcellular_component
GO:0000794condensed nuclear chromosomeISScellular_component
GO:0045177apical part of cellIEAcellular_component
GO:0005829cytosolTAScellular_component
GO:0000226microtubule cytoskeleton organizationTASbiological_process
GO:0000212meiotic spindle organizationISSbiological_process
GO:0005813centrosomeIDAcellular_component
GO:0051258protein polymerizationIEAbiological_process
GO:0031252cell leading edgeIEAcellular_component
GO:0005876spindle microtubuleIEAcellular_component
GO:0000930gamma-tubulin complexTAScellular_component
GO:0000794condensed nuclear chromosomeIEAcellular_component
GO:0005827polar microtubuleIDAcellular_component
GO:0000242pericentriolar materialIEAcellular_component
GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0005200structural constituent of cytoskeletonTASmolecular_function
GO:0043234protein complexIEAcellular_component
GO:0000930gamma-tubulin complexIEAcellular_component
GO:0003924GTPase activityIEAmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005737cytoplasmISScellular_component
GO:0006184GTP catabolic processIEAbiological_process
GO:0000212meiotic spindle organizationIEAbiological_process
GO:0000278mitotic cell cycleTASbiological_process