Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:STK38_HUMAN
Description:serine/threonine kinase 38 [Source:HGNC Symbol;Acc:17847]
Location:chr6 p21.31
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y443WVFINyTYKRFPkinase_CPhosphoSitePlus
T444VFINYtYKRFEPkinase_CPhosphoSitePlus
S264FQNMNsKRKAEHPRD
T452RFEGLtARGAIPhosphoSitePlus
T26TMTKVtLENFYRegPhos
Y460GAIPSyMKAAKPhosphoSitePlus
T74HARKEtEFLRLNDR1RegPhos
S281RQLAFsTVGTPPkinasePhosphoSitePlus
S6MAMTGsTPCSSPhosphoSitePlus
T285FSTVGtPDYIAHPRD; phosphoELM
T74HARKEtEFLRLSTK38HPRD
T282QLAFStVGTPDPkinasePhosphoSitePlus
S10GSTPCsSMSNHPhosphoSitePlus
S281RQLAFsTVGTPNDR1phosphoELM; RegPhos
T444VFINYtYKRFENDR1RegPhos
Y31TLENFySNLIAAlpha-2-MRAP_NPhosphoSitePlus
T285FSTVGtPDYIAPkinasePhosphoSitePlus
T7AMTGStPCSSMPhosphoSitePlus
T26TMTKVtLENFYAlpha-2-MRAP_NPhosphoSitePlus
T235DFGLCtGLKKAPkinasePhosphoSitePlus
Y445FINYTyKRFEGPkinase_CPhosphoSitePlus
S264FQNMNsKRKAEPkinasePhosphoSitePlus
S32LENFYsNLIAQAlpha-2-MRAP_NPhosphoSitePlus
T74HARKEtEFLRLPhosphoSitePlus; RegPhos
S281RQLAFsTVGTPautocatalysisRegPhos
T444VFINYtYKRFESTK38HPRD
T444VFINYtYKRFEphosphoELM; RegPhos
S11STPCSsMSNHTPhosphoSitePlus
S281RQLAFsTVGTPSTK38HPRD

Dephosphorylation site
STK38_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000229812E18KGreenman2007Skin Cancer17344846, 18428421

Differential expressed protein
STK38_HUMAN is not differential expressed protein.

Hyperphosphorylation site
STK38_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK38_HUMANENC2_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANSTK38_HUMANkinase -> substrateRegPhos
STK38_HUMANBPL1_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANSRC8_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANMK07_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANRD23B_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANIASPP_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANIF4A3_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANMTA1_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANSTK38_HUMANkinase -> substrateRegPhos
STK38_HUMANMED28_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANMDM2_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANNFAC4_HUMANkinase -> substrateRobert H Newman (2013)
STK38_HUMANCDCA5_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
STK38_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004674protein serine/threonine kinase activityIDAmolecular_function
GO:0043407negative regulation of MAP kinase activityIDAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0031435mitogen-activated protein kinase kinase kinase binIPImolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005524ATP bindingIDAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0070688MLL5-L complexIDAcellular_component
GO:0005886plasma membraneIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0007243intracellular protein kinase cascadeIDAbiological_process
GO:0006464cellular protein modification processIDAbiological_process
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0000287magnesium ion bindingIDAmolecular_function
GO:0006468protein phosphorylationIDAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function


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