Phosphorylation

Protein information

UniProt/SwissProt ID:	STK38_HUMAN
Description:	serine/threonine kinase 38 [Source:HGNC Symbol;Acc:17847]
Location:	chr6 p21.31
Node attribute:	kinase; substrate

Position	PhosphoPeptide	Catalytic kinase	Source
Y443	WVFINyTYKRF	Pkinase_C	PhosphoSitePlus
T444	VFINYtYKRFE	Pkinase_C	PhosphoSitePlus
S264	FQNMNsKRKAE		HPRD
T452	RFEGLtARGAI		PhosphoSitePlus
T26	TMTKVtLENFY		RegPhos
Y460	GAIPSyMKAAK		PhosphoSitePlus
T74	HARKEtEFLRL	NDR1	RegPhos
S281	RQLAFsTVGTP	Pkinase	PhosphoSitePlus
S6	MAMTGsTPCSS		PhosphoSitePlus
T285	FSTVGtPDYIA		HPRD; phosphoELM
T74	HARKEtEFLRL	STK38	HPRD
T282	QLAFStVGTPD	Pkinase	PhosphoSitePlus
S10	GSTPCsSMSNH		PhosphoSitePlus
S281	RQLAFsTVGTP	NDR1	phosphoELM; RegPhos
T444	VFINYtYKRFE	NDR1	RegPhos
Y31	TLENFySNLIA	Alpha-2-MRAP_N	PhosphoSitePlus
T285	FSTVGtPDYIA	Pkinase	PhosphoSitePlus
T7	AMTGStPCSSM		PhosphoSitePlus
T26	TMTKVtLENFY	Alpha-2-MRAP_N	PhosphoSitePlus
T235	DFGLCtGLKKA	Pkinase	PhosphoSitePlus
Y445	FINYTyKRFEG	Pkinase_C	PhosphoSitePlus
S264	FQNMNsKRKAE	Pkinase	PhosphoSitePlus
S32	LENFYsNLIAQ	Alpha-2-MRAP_N	PhosphoSitePlus
T74	HARKEtEFLRL		PhosphoSitePlus; RegPhos
S281	RQLAFsTVGTP	autocatalysis	RegPhos
T444	VFINYtYKRFE	STK38	HPRD
T444	VFINYtYKRFE		phosphoELM; RegPhos
S11	STPCSsMSNHT		PhosphoSitePlus
S281	RQLAFsTVGTP	STK38	HPRD

STK38_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000229812	E18K	Greenman2007	Skin Cancer	17344846, 18428421

STK38_HUMAN is not differential expressed protein.

STK38_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
STK38_HUMAN	ENC2_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	STK38_HUMAN	kinase -> substrate	RegPhos
STK38_HUMAN	BPL1_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	SRC8_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	RD23B_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	IASPP_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	IF4A3_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	MTA1_HUMAN	kinase -> substrate	Robert H Newman (2013)
ZAGL2_HUMAN	STK38_HUMAN	kinase -> substrate	RegPhos
STK38_HUMAN	MED28_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	MDM2_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
STK38_HUMAN	CDCA5_HUMAN	kinase -> substrate	Robert H Newman (2013)

KEGG Pathway

STK38_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0004674	protein serine/threonine kinase activity	IDA	molecular_function
GO:0043407	negative regulation of MAP kinase activity	IDA	biological_process
GO:0016772	transferase activity, transferring phosphorus-cont	IEA	molecular_function
GO:0004672	protein kinase activity	IEA	molecular_function
GO:0031435	mitogen-activated protein kinase kinase kinase bin	IPI	molecular_function
GO:0005737	cytoplasm	IDA	cellular_component
GO:0005515	protein binding	IPI	molecular_function
GO:0005524	ATP binding	IDA	molecular_function
GO:0005515	protein binding	IEA	molecular_function
GO:0070688	MLL5-L complex	IDA	cellular_component
GO:0005886	plasma membrane	IDA	cellular_component
GO:0005634	nucleus	IDA	cellular_component
GO:0007243	intracellular protein kinase cascade	IDA	biological_process
GO:0006464	cellular protein modification process	IDA	biological_process
GO:0043231	intracellular membrane-bounded organelle	IDA	cellular_component
GO:0000287	magnesium ion binding	IDA	molecular_function
GO:0006468	protein phosphorylation	IDA	biological_process
GO:0004713	protein tyrosine kinase activity	IEA	molecular_function

Human Phosphorylation Mediated
Signaling Transduction Network