| UniProt/SwissProt ID: | S1PR2_HUMAN |
| Description: | Sphingosine 1-phosphate receptor 2 [Source:UniProtKB/Swiss-Prot;Acc:O95136] |
| Location: | chr19 p13.2 |
| Node attribute: | GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S343 | MHMPTsPTFLE | PhosphoSitePlus | |
| S333 | LRSSSsLERGM | PhosphoSitePlus | |
| Dephosphorylation site |
| S1PR2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| S1PR2_HUMAN do not have mutation site. |
| Differential expressed protein |
| S1PR2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| S1PR2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| S1PR2_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| S1PR2_HUMAN | GNA11_HUMAN | GPCR -> Gprotein | gpDB |
| S1PR2_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| S1PR2_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| S1PR2_HUMAN | GNA13_HUMAN | GPCR -> Gprotein | gpDB |
| S1PR2_HUMAN | GNA12_HUMAN | GPCR -> Gprotein | gpDB |
| S1PR2_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| S1PR2_HUMAN | GNAQ_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007610 | behavior | IEA | biological_process |
| GO:0008284 | positive regulation of cell proliferation | TAS | biological_process |
| GO:0000187 | activation of MAPK activity | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0038036 | sphingosine-1-phosphate receptor activity | IEA | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0008289 | lipid binding | TAS | molecular_function |