Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RAP1A_HUMAN
Description:RAP1A, member of RAS oncogene family [Source:HGNC Symbol;Acc:9855]
Location:chr1 p13.2
Node attribute:PPI(source); substrate; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S11LVVLGsGGVGKRasPhosphoSitePlus
S180KPKKKsCLLL_PhosphoSitePlus
S11LVVLGsGGVGKHPRD
Y159VNEIFyDLVRQRasPhosphoSitePlus
S180KPKKKsCLPRKACAHPRD
S180KPKKKsCLLLPKA_groupRegPhos
S180KPKKKsCLLLPKACaRegPhos
S39PTIEDsYRKQVRasPhosphoSitePlus
S180KPKKKsCLPKA_groupphosphoELM

Dephosphorylation site
RAP1A_HUMAN do not have dephosphorylation site.

Mutation site
RAP1A_HUMAN do not have mutation site.

Differential expressed protein
RAP1A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RAP1A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
YES_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
KKCC2_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
OXSR1_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
PIM1_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
FGFR4_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
STK16_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
MK07_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANRAP1A_HUMANkinase -> substrateKEGG; HPRD
M3K7_HUMANRAP1A_HUMANkinase -> substrateRobert H Newman (2013)
RAP1A_HUMANBRAF_HUMANotherKEGG
RAP1A_HUMANMK08_HUMANotherKEGG
RPGF1_HUMANRAP1A_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04010MAPK signaling pathway
hsa04510Focal adhesion
hsa04722Neurotrophin signaling pathway
hsa04670Leukocyte transendothelial migration
hsa04720Long-term potentiation
hsa05211Renal cell carcinoma
hsa04062Chemokine signaling pathway
hsa04972Pancreatic secretion

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006913nucleocytoplasmic transportIEAbiological_process
GO:0017016Ras GTPase bindingIEAmolecular_function
GO:0006184GTP catabolic processIEAbiological_process
GO:0032045guanyl-nucleotide exchange factor complexIEAcellular_component
GO:0008283cell proliferationIEAbiological_process
GO:0006886intracellular protein transportIEAbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0003924GTPase activityIEAmolecular_function
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0007165signal transductionTASbiological_process
GO:0015031protein transportIEAbiological_process
GO:0000186activation of MAPKK activityTASbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0005886plasma membraneTAScellular_component
GO:0007596blood coagulationTASbiological_process
GO:0030168platelet activationTASbiological_process
GO:0050796regulation of insulin secretionTASbiological_process
GO:0006112energy reserve metabolic processTASbiological_process
GO:0007264small GTPase mediated signal transductionIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016020membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function


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