Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GNAT1_HUMAN
Description:guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 [Source:HGNC Symbol;Acc:4393]
Location:chr3 p21.31
Node attribute:Gprotein; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S130RLWKDsGIQACG-alphaPhosphoSitePlus
Y142ERASEyQLNDSSRCRegPhos

Dephosphorylation site
GNAT1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000387555E314DTCGAOvarian Cancer21720365, 18772890
ENSP00000387555E314DCOSMICOvarian Cancer21720365
ENSP00000232461E314DCOSMICOvarian Cancer21720365
ENSP00000232461K47QCOSMICOvarian Cancer21720365
ENSP00000232461A334TCOSMICHead and Neck Cancer21798893
ENSP00000387555K47QCOSMICOvarian Cancer21720365
ENSP00000232461E314DTCGAOvarian Cancer21720365, 18772890
ENSP00000387555A334TCOSMICHead and Neck Cancer21798893

Differential expressed protein
GNAT1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GNAT1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FZD2_HUMANGNAT1_HUMANGPCR -> GproteingpDB
OPN3_HUMANGNAT1_HUMANGPCR -> GproteingpDB
OPN4_HUMANGNAT1_HUMANGPCR -> GproteingpDB
OPSD_HUMANGNAT1_HUMANGPCR -> GproteingpDB
OPSX_HUMANGNAT1_HUMANGPCR -> GproteingpDB
OPSB_HUMANGNAT1_HUMANGPCR -> GproteingpDB
GNAT1_HUMANPDE6A_HUMANGprotein -> effectorgpDB
GNAT1_HUMANCNRG_HUMANGprotein -> effectorgpDB
GNAT1_HUMANPDE6B_HUMANGprotein -> effectorgpDB
GNAT1_HUMANCNCG_HUMANGprotein -> effectorgpDB
SRC_HUMANGNAT1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04744Phototransduction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043025neuronal cell bodyIEAcellular_component
GO:0007188adenylate cyclase-modulating G-protein coupled recIBAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0007602phototransductionIEAbiological_process
GO:0000035acyl bindingISSmolecular_function
GO:0008283cell proliferationIEAbiological_process
GO:0007601visual perceptionIEAbiological_process
GO:0007603phototransduction, visible lightIMPbiological_process
GO:0050917sensory perception of umami tasteIEAbiological_process
GO:0031683G-protein beta/gamma-subunit complex bindingIEAmolecular_function
GO:0001580detection of chemical stimulus involved in sensoryIEAbiological_process
GO:0009416response to light stimulusISSbiological_process
GO:0007601visual perceptionTASbiological_process
GO:0031234extrinsic to internal side of plasma membraneIBAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0051343positive regulation of cyclic-nucleotide phosphodiIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0042622photoreceptor outer segment membraneISScellular_component
GO:0019901protein kinase bindingISSmolecular_function
GO:0001664G-protein coupled receptor bindingIBAmolecular_function
GO:0051344negative regulation of cyclic-nucleotide phosphodiISSbiological_process
GO:0019001guanyl nucleotide bindingIEAmolecular_function
GO:0006184GTP catabolic processIEAbiological_process
GO:0004871signal transducer activityIEAmolecular_function
GO:0001750photoreceptor outer segmentIEAcellular_component
GO:0016056rhodopsin mediated signaling pathwayIEAbiological_process
GO:0019003GDP bindingISSmolecular_function
GO:0071257cellular response to electrical stimulusIEAbiological_process
GO:0003924GTPase activityIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0009642response to light intensityIEAbiological_process
GO:0005834heterotrimeric G-protein complexIBAcellular_component
GO:0050908detection of light stimulus involved in visual perIEAbiological_process
GO:0016324apical plasma membraneIEAcellular_component
GO:0001917photoreceptor inner segmentIEAcellular_component
GO:0042462eye photoreceptor cell developmentIEAbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0060041retina development in camera-type eyeIEAbiological_process
GO:0016020membraneNAScellular_component
GO:0032391photoreceptor connecting ciliumIEAcellular_component
GO:0007165signal transductionNASbiological_process