| UniProt/SwissProt ID: | OPN4_HUMAN |
| Description: | opsin 4 [Source:HGNC Symbol;Acc:14449] |
| Location: | chr10 q23.2 |
| Node attribute: | GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S391 | RSTHRsTLTSH | PhosphoSitePlus | |
| S379 | VSRRHsRPYPS | PhosphoSitePlus | |
| T392 | STHRStLTSHT | PhosphoSitePlus | |
| T397 | TLTSHtSNLSW | PhosphoSitePlus | |
| Dephosphorylation site |
| OPN4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000361141 | W212* | COSMIC | Ovarian Cancer | 21720365 | ENSP00000361141 | K304N | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000361141 | K304N | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| OPN4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| OPN4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| OPN4_HUMAN | GNAT1_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| OPN4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0007602 | phototransduction | IEA | biological_process |
| GO:0007601 | visual perception | IEA | biological_process |
| GO:0018298 | protein-chromophore linkage | IEA | biological_process |
| GO:0007602 | phototransduction | IDA | biological_process |
| GO:0009584 | detection of visible light | IDA | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005502 | 11-cis retinal binding | IDA | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0008020 | G-protein coupled photoreceptor activity | IEA | molecular_function |
| GO:0016021 | integral to membrane | TAS | cellular_component |
| GO:0042752 | regulation of circadian rhythm | ISS | biological_process |
| GO:0042752 | regulation of circadian rhythm | IEA | biological_process |
| GO:0008020 | G-protein coupled photoreceptor activity | IDA | molecular_function |
| GO:0048511 | rhythmic process | IEA | biological_process |