| UniProt/SwissProt ID: | OPSX_HUMAN |
| Description: | retinal pigment epithelium-derived rhodopsin homolog [Source:HGNC Symbol;Acc:10450] |
| Location: | chr4 q25 |
| Node attribute: | GPCR |
| Phosphorylation site |
| OPSX_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| OPSX_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000314992 | V319L | COSMIC | Ovarian Cancer | 21720365 | ENSP00000314992 | R302Q | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000314992 | V319L | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| OPSX_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| OPSX_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| OPSX_HUMAN | GNAT1_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| OPSX_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007601 | visual perception | IEA | biological_process |
| GO:0018298 | protein-chromophore linkage | IEA | biological_process |
| GO:0009881 | photoreceptor activity | IEA | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007602 | phototransduction | IEA | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |