Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CNRG_HUMAN
Description:phosphodiesterase 6G, cGMP-specific, rod, gamma [Source:HGNC Symbol;Acc:8789]
Location:chr17 q25.3
Node attribute:effector; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T62MEGLGtDITVIBARK1RegPhos
T62MEGLGtDITVIGRK-2phosphoELM
T62MEGLGtDITVIBARK1(GRK2RegPhos
T62MEGLGtDITVIADRBK1HPRD
T22AGGPVtPRKGPMAPK3HPRD
T22AGGPVtPRKGPPDE6_gammaPhosphoSitePlus
T22AGGPVtPRKGPErk1RegPhos

Dephosphorylation site
CNRG_HUMAN do not have dephosphorylation site.

Mutation site
CNRG_HUMAN do not have mutation site.

Differential expressed protein
CNRG_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CNRG_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GNAT1_HUMANCNRG_HUMANGprotein -> effectorgpDB
ARBK1_HUMANCNRG_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)
MK03_HUMANCNRG_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa00230Purine metabolism
hsa04744Phototransduction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:00475553',5'-cyclic-GMP phosphodiesterase activityIEAmolecular_function
GO:0007601visual perceptionIEAbiological_process
GO:0000187activation of MAPK activityIEAbiological_process
GO:0004857enzyme inhibitor activityTASmolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0045742positive regulation of epidermal growth factor recIEAbiological_process
GO:0043086negative regulation of catalytic activityTASbiological_process
GO:0045745positive regulation of G-protein coupled receptor IEAbiological_process
GO:0005829cytosolTAScellular_component
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activityIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0030553cGMP bindingIEAmolecular_function


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