Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PDE6B_HUMAN
Description:phosphodiesterase 6B, cGMP-specific, rod, beta [Source:HGNC Symbol;Acc:8786]
Location:chr4 p16.3
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y556YRRITyHNWRHPDEase_IPhosphoSitePlus
Y219NFATLyLKIYHGAFPhosphoSitePlus
Y227IYHLSyLHNCEPhosphoSitePlus
Y402GVATFyNRKDGGAFPhosphoSitePlus
Y212DVFLKyLNFATGAFPhosphoSitePlus
T715MAMMMtACDLSPDEase_IPhosphoSitePlus
S226KIYHLsYLHNCPhosphoSitePlus

Dephosphorylation site
PDE6B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000255622S376TBIOMARTBreast Cancer21930507, 21930502
ENSP00000420295S376TBIOMARTBreast Cancer21930507, 21930502
ENSP00000255622T703KBIOMARTBreast Cancer21930507, 21930502
ENSP00000420295R20LBIOMARTBreast Cancer21930507, 21930502
ENSP00000420295T703KBIOMARTBreast Cancer21930507, 21930502
ENSP00000255622R20LBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
PDE6B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PDE6B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GNAT1_HUMANPDE6B_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04744Phototransduction
hsa00230Purine metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0046037GMP metabolic processIMPbiological_process
GO:0051480cytosolic calcium ion homeostasisIMPbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0007165signal transductionIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0009583detection of light stimulusIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0007603phototransduction, visible lightTASbiological_process
GO:00475553',5'-cyclic-GMP phosphodiesterase activityIMPmolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0003824catalytic activityIEAmolecular_function
GO:0007601visual perceptionIEAbiological_process
GO:0060041retina development in camera-type eyeIEAbiological_process
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activityIEAmolecular_function


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