| UniProt/SwissProt ID: | CNCG_HUMAN |
| Description: | phosphodiesterase 6H, cGMP-specific, cone, gamma [Source:HGNC Symbol;Acc:8790] |
| Location: | chr12 p12.3 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S2 | ____MsDNTTL | Involucrin_N; PDE6_gamma | PhosphoSitePlus |
| T6 | MSDNTtLPAPA | Involucrin_N; PDE6_gamma | PhosphoSitePlus |
| Dephosphorylation site |
| CNCG_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000266395 | A9V | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| CNCG_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CNCG_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GNAT1_HUMAN | CNCG_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa00230 | Purine metabolism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0045745 | positive regulation of G-protein coupled receptor | IEA | biological_process |
| GO:0004857 | enzyme inhibitor activity | TAS | molecular_function |
| GO:0030553 | cGMP binding | IEA | molecular_function |
| GO:0007601 | visual perception | IEA | biological_process |
| GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | IEA | molecular_function |
| GO:0045742 | positive regulation of epidermal growth factor rec | IEA | biological_process |
| GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity | IEA | molecular_function |
| GO:0000187 | activation of MAPK activity | IEA | biological_process |
| GO:0043086 | negative regulation of catalytic activity | TAS | biological_process |
| GO:0050896 | response to stimulus | IEA | biological_process |