Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:VIP_HUMAN
Description:vasoactive intestinal peptide [Source:HGNC Symbol;Acc:12693]
Location:chr6 q25.2
Node attribute:ligand; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S116VSSNIsEDPVPPhosphoSitePlus
Y29SAWPLyRAPSAPhosphoSitePlus
S105KKYLEsLMGKRHormone_2PhosphoSitePlus

Dephosphorylation site
VIP_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000356213P42LCOSMICSkin Cancer21984974

Differential expressed protein
VIP_HUMAN is not differential expressed protein.

Hyperphosphorylation site
VIP_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
VIP_HUMANVIPR1_HUMANligand -> receptorHPMR
VIP_HUMANVIPR2_HUMANligand -> receptorHPMR
CREB1_HUMANVIP_HUMANTF -> target geneTRANSFAC
JUN_HUMANVIP_HUMANTF -> target geneTRANSFAC
ATF2_HUMANVIP_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
VIP_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005102receptor bindingIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0001938positive regulation of endothelial cell proliferatIEAbiological_process
GO:0048662negative regulation of smooth muscle cell proliferIEAbiological_process
GO:0043025neuronal cell bodyIEAcellular_component
GO:0007589body fluid secretionTASbiological_process
GO:0045909positive regulation of vasodilationIEAbiological_process
GO:0032880regulation of protein localizationIEAbiological_process
GO:0009966regulation of signal transductionIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0043267negative regulation of potassium ion transportIEAbiological_process
GO:0005184neuropeptide hormone activityTASmolecular_function
GO:0005179hormone activityIEAmolecular_function
GO:0007611learning or memoryIEAbiological_process
GO:0010579positive regulation of adenylate cyclase activity IEAbiological_process
GO:0045732positive regulation of protein catabolic processIDAbiological_process
GO:0005179hormone activityIDAmolecular_function
GO:0008284positive regulation of cell proliferationTASbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0051930regulation of sensory perception of painIEAbiological_process
GO:0045732positive regulation of protein catabolic processIEAbiological_process
GO:0010579positive regulation of adenylate cyclase activity IDAbiological_process
GO:0032880regulation of protein localizationIDAbiological_process


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