| UniProt/SwissProt ID: | VIPR2_HUMAN |
| Description: | vasoactive intestinal peptide receptor 2 [Source:HGNC Symbol;Acc:12695] |
| Location: | chr7 q36.3 |
| Node attribute: | receptor; GPCR |
| Phosphorylation site |
| VIPR2_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| VIPR2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000262178 | H28L | COSMIC | Ovarian Cancer | 21720365 | ENSP00000262178 | V200M | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000262178 | S187Y | COSMIC | Lung Cancer | 20016488 |
| Differential expressed protein |
| VIPR2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| VIPR2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| VIP_HUMAN | VIPR2_HUMAN | ligand -> receptor | HPMR |
| VIPR2_HUMAN | GNAS2_HUMAN | GPCR -> Gprotein | gpDB |
| VIPR2_HUMAN | GNAS1_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0048662 | negative regulation of smooth muscle cell prolifer | IEA | biological_process |
| GO:0007190 | activation of adenylate cyclase activity | IEA | biological_process |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007166 | cell surface receptor signaling pathway | IEA | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0004888 | transmembrane signaling receptor activity | IEA | molecular_function |
| GO:0004999 | vasoactive intestinal polypeptide receptor activit | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |