| UniProt/SwissProt ID: | STK40_HUMAN |
| Description: | serine/threonine kinase 40 [Source:HGNC Symbol;Acc:21373] |
| Location: | chr1 p34.3 |
| Node attribute: | kinase |
| Phosphorylation site |
| STK40_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| STK40_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000362224 | M133T | Greenman2007 | Intestines Cancer | 17344846 | ENSP00000362221 | M133T | HPI | Colorectal Cancer | 17344846 | ENSP00000362224 | Q271* | Greenman2007 | Neoplasms by Histologic Type | 17344846 | ENSP00000362221 | R211Q | HPI | Colorectal Cancer | 17344846 | ENSP00000362221 | R211Q | Greenman2007 | Intestines Cancer | 17344846 | ENSP00000362224 | R211Q | HPI | Colorectal Cancer | 17344846 | ENSP00000362224 | M133T | HPI | Colorectal Cancer | 17344846 | ENSP00000362221 | M133T | Greenman2007 | Intestines Cancer | 17344846 | ENSP00000362224 | R211Q | Greenman2007 | Intestines Cancer | 17344846 | ENSP00000362221 | Q271* | Greenman2007 | Neoplasms by Histologic Type | 17344846 |
| Differential expressed protein |
| STK40_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| STK40_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| STK40_HUMAN | IASPP_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | BPL1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | PSA6_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | MBNL3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | NDF1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | RFC5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | MTA1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | ZN363_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK40_HUMAN | IRF3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| STK40_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |