Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:REL_HUMAN
Description:v-rel reticuloendotheliosis viral oncogene homolog (avian) [Source:HGNC Symbol;Acc:9954]
Location:chr2 p16.1
Node attribute:gene; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y359IGEGRyFKKEPPhosphoSitePlus
S386SSQAEsYYPSPPhosphoSitePlus
Y88DCRDGyYEAEFRHDPhosphoSitePlus
Y597VQDSQySGIGSPhosphoSitePlus
Y6MASGAyNPYIEPhosphoSitePlus
S523NLENPsCNSVLPhosphoSitePlus
S557TTVFVsQSDAFPhosphoSitePlus
Y47DNNRTyPSIQIRHDPhosphoSitePlus
S503MMTTSsDSMGEPhosphoSitePlus
Y176VSNPIyDNRAPRHDPhosphoSitePlus
S526NPSCNsVLDPRPhosphoSitePlus
Y89CRDGYyEAEFGRHDPhosphoSitePlus
Y387SQAESyYPSPGPhosphoSitePlus
S492DPNMLsNCSVNPhosphoSitePlus; phosphoELM

Dephosphorylation site
REL_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000295025V451ICOSMICBreast Cancer20668451
ENSP00000295025G423DCOSMICSkin Cancer21984974
ENSP00000295025P8SCOSMICSkin Cancer21984974
ENSP00000295025E38QTCGAOvarian Cancer21720365, 18772890
ENSP00000295025E38QCOSMICOvarian Cancer21720365
ENSP00000295025S479*COSMICHead and Neck Cancer21798893
ENSP00000295025*620YCOSMICIntestines Cancer16959974

Differential expressed protein
REL_HUMAN is not differential expressed protein.

Hyperphosphorylation site
REL_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
REL_HUMANB2LA1_HUMANTF -> target geneTRANSFAC
REL_HUMANIL2RA_HUMANTF -> target geneTRANSFAC
AP2A_HUMANREL_HUMANTF -> target geneTRANSFAC
REL_HUMANIFNB_HUMANTF -> target geneTRANSFAC
REL_HUMANIL12B_HUMANTF -> target geneTRANSFAC
SP1_HUMANREL_HUMANTF -> target geneTRANSFAC
REL_HUMANTNFA_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
REL_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001816cytokine productionIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cIEPbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005829cytosolTAScellular_component
GO:0045084positive regulation of interleukin-12 biosyntheticIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005515protein bindingIPImolecular_function


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