Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTN2_HUMAN
Description:protein tyrosine phosphatase, non-receptor type 2 [Source:HGNC Symbol;Acc:9650]
Location:chr18 p11.21
Node attribute:substrate; phosphotase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S304PAFDHsPNKIMCDK1HPRD; SysPTM
S304PAFDHsPNKIMPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y22RWQPLyLEIRNPhosphoSitePlus
S298SKEDLsPAFDHPhosphoSitePlus; HPRD; phosphoELM
S304PAFDHsPNKIMCDK2HPRD; SysPTM
Y32NESHDyPHRVAPhosphoSitePlus
S52RYRDVsPYDHSY_phosphatasePhosphoSitePlus
S304PAFDHsPNKIMCDK5HPRD; SysPTM
T340SKMQDtMEENSIKKbetaNEMObind; YL1; SynPhosphoSitePlus
Y384RKRWLyWQPILSynaptobrevinPhosphoSitePlus
Y54RDVSPyDHSRVY_phosphatasePhosphoSitePlus
T261MGLIQtPDQLRY_phosphatasePhosphoSitePlus
S293RWKELsKEDLSPhosphoSitePlus
S72DYINAsLVDIEY_phosphatase; CHASE3PhosphoSitePlus
T310PNKIMtEKYNGPhosphoSitePlus

Dephosphorylation site
PTN2_HUMAN do not have dephosphorylation site.

Mutation site
PTN2_HUMAN do not have mutation site.

Differential expressed protein
PTN2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTN2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK1_HUMANPTN2_HUMANkinase -> substrateHPRD
CDK2_HUMANPTN2_HUMANkinase -> substrateHPRD
CDK5_HUMANPTN2_HUMANkinase -> substrateHPRD
PTN2_HUMANSTAT1_HUMANphosphatase -> substrateHPRD
PTN2_HUMANSRC_HUMANphosphatase -> substrateHPRD
PTN2_HUMANPGFRB_HUMANphosphatase -> substrateHPRD
PTN2_HUMANJAK1_HUMANphosphatase -> substrateHPRD
PTN2_HUMANINSR_HUMANphosphatase -> substrateHPRD
PTN2_HUMANSHC1_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
PTN2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005783endoplasmic reticulumIDAcellular_component
GO:0006470protein dephosphorylationTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0006470protein dephosphorylationIEAbiological_process
GO:0016791phosphatase activityIEAmolecular_function
GO:0060334regulation of interferon-gamma-mediated signaling TASbiological_process
GO:0004726non-membrane spanning protein tyrosine phosphataseIEAmolecular_function
GO:0004725protein tyrosine phosphatase activityIEAmolecular_function
GO:0035335peptidyl-tyrosine dephosphorylationTASbiological_process
GO:0016311dephosphorylationIEAbiological_process
GO:0008286insulin receptor signaling pathwayIEAbiological_process
GO:0060333interferon-gamma-mediated signaling pathwayTASbiological_process


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