Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MT2_HUMAN
Description:metallothionein 2A [Source:HGNC Symbol;Acc:7406]
Location:chr16 q12.2
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S6MDPNCsCAAGDMetallothioPhosphoSitePlus; SysPTM
S6AAGDHPRD; SysPTM

Dephosphorylation site
MT2_HUMAN do not have dephosphorylation site.

Mutation site
MT2_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000245185Breast CancerNormal vs. Cancercell lineUp1.520543960
ENSP00000245185Breast CancerNormal vs. Cancercell lineUp1.820543960

Hyperphosphorylation site
MT2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AP2A_HUMANMT2_HUMANTF -> target geneTRANSFAC
MTF1_HUMANMT2_HUMANTF -> target geneTRANSFAC
SP1_HUMANMT2_HUMANTF -> target geneTRANSFAC
TFAP4_HUMANMT2_HUMANTF -> target geneTRANSFAC
FOS_HUMANMT2_HUMANTF -> target geneTRANSFAC
JUN_HUMANMT2_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
MT2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0036018cellular response to erythropoietinIEPbiological_process
GO:0035690cellular response to drugIDAbiological_process
GO:0006878cellular copper ion homeostasisTASbiological_process
GO:0060333interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0008144drug bindingIDAmolecular_function
GO:0005829cytosolTAScellular_component
GO:0048471perinuclear region of cytoplasmISScellular_component
GO:0005737cytoplasmISScellular_component
GO:0045926negative regulation of growthISSbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0071294cellular response to zinc ionIEPbiological_process
GO:0008270zinc ion bindingISSmolecular_function
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0036016cellular response to interleukin-3IEPbiological_process
GO:0005634nucleusISScellular_component


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