Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MTF1_HUMAN
Description:metal-regulatory transcription factor 1 [Source:HGNC Symbol;Acc:7428]
Location:chr1 p34.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y151GCPRTySTAGNzf-C2H2PhosphoSitePlus
Y215AFNTLyRLKAHzf-C2H2PhosphoSitePlus
T252RKHIRtHTGEKzf-C2H2PhosphoSitePlus
S39GLVPSsSGTVYPhosphoSitePlus
Y140KEVKRyQCTFEHPRD; phosphoELM
S620QQIGLsVPVIIPhosphoSitePlus
S305FSTQYsLKSHMzf-C2H2PhosphoSitePlus
T254HIRTHtGEKPFPhosphoSitePlus
Y140KEVKRyQCTFEzf-C2H2PhosphoSitePlus

Dephosphorylation site
MTF1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000362127G255RCOSMICOvarian Cancer21720365
ENSP00000362127Q161HCOSMICPancreatic Cancer

Differential expressed protein
MTF1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MTF1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MTF1_HUMANMT2_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
MTF1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0035035histone acetyltransferase bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005622intracellularIEAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0046686response to cadmium ionIEAbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0010038response to metal ionTASbiological_process
GO:0006979response to oxidative stressIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0001047core promoter bindingIDAmolecular_function
GO:0000979RNA polymerase II core promoter sequence-specific IEAmolecular_function
GO:0003713transcription coactivator activityTASmolecular_function
GO:0006357regulation of transcription from RNA polymerase IITASbiological_process


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