| UniProt/SwissProt ID: | MT2_HUMAN |
| Description: | metallothionein 2A [Source:HGNC Symbol;Acc:7406] |
| Location: | chr16 q12.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S6 | MDPNCsCAAGD | Metallothio | PhosphoSitePlus; SysPTM |
| S6 | AAGD | HPRD; SysPTM | |
| Dephosphorylation site |
| MT2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| MT2_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000245185 | Breast Cancer | Normal vs. Cancer | cell line | Up | 1.5 | 20543960 | ENSP00000245185 | Breast Cancer | Normal vs. Cancer | cell line | Up | 1.8 | 20543960 |
| Hyperphosphorylation site |
| MT2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| AP2A_HUMAN | MT2_HUMAN | TF -> target gene | TRANSFAC |
| MTF1_HUMAN | MT2_HUMAN | TF -> target gene | TRANSFAC |
| SP1_HUMAN | MT2_HUMAN | TF -> target gene | TRANSFAC |
| TFAP4_HUMAN | MT2_HUMAN | TF -> target gene | TRANSFAC |
| FOS_HUMAN | MT2_HUMAN | TF -> target gene | TRANSFAC |
| JUN_HUMAN | MT2_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| MT2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0036018 | cellular response to erythropoietin | IEP | biological_process |
| GO:0035690 | cellular response to drug | IDA | biological_process |
| GO:0006878 | cellular copper ion homeostasis | TAS | biological_process |
| GO:0060333 | interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0008144 | drug binding | IDA | molecular_function |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0048471 | perinuclear region of cytoplasm | ISS | cellular_component |
| GO:0005737 | cytoplasm | ISS | cellular_component |
| GO:0045926 | negative regulation of growth | ISS | biological_process |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0071294 | cellular response to zinc ion | IEP | biological_process |
| GO:0008270 | zinc ion binding | ISS | molecular_function |
| GO:0019221 | cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0036016 | cellular response to interleukin-3 | IEP | biological_process |
| GO:0005634 | nucleus | ISS | cellular_component |