Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:KSR1_HUMAN
Description:kinase suppressor of ras 1 [Source:HGNC Symbol;Acc:6465]
Location:chr17 q11.1
Node attribute:kinase; effector; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T423EPHFGtLPKALPkinasePhosphoSitePlus
S312SKSHEsQLGNRPhosphoSitePlus
Y721IKGMGyLHAKGPhosphoSitePlus
S291TPPPPsRKVFQPhosphoSitePlus
S265PRALHsFITPPPhosphoSitePlus
S886LNRRLsHPGHFPhosphoSitePlus
T402TRLRRtESVPSphosphoELM
S227GPRSIsVSALPPhosphoSitePlus
S595ISRKAsQTSVYPkinasePhosphoSitePlus
S236LPASDsPTPSFPhosphoSitePlus
Y160CGRLQyALTCLPhosphoSitePlus
T248EGLSDtCIPLHPhosphoSitePlus
S567PEAGKsEAEDDphosphoELM
T471PSSATtPPNPSPkinasePhosphoSitePlus
S329MRFDLsHGSPQPhosphoSitePlus
S307PTLTRsKSHESPhosphoSitePlus
T238ASDSPtPSFSEPhosphoSitePlus
S404LRRTEsVPSDIPkinasePhosphoSitePlus
S404LRRTEsVPSDIphosphoELM
S404LRRTEsVPSDIMARK3RegPhos
S255IPLHAsGRLTPPhosphoSitePlus
T268LHSFItPPTTPPhosphoSitePlus; phosphoELM; SysPTM
S567PEAGKsEAEDDPkinasePhosphoSitePlus
S309LTRSKsHESQLPhosphoSitePlus; phosphoELM; RegPhos; SysPTM
T402TRLRRtESVPSPkinasePhosphoSitePlus
T286LKPPRtPPPPSPhosphoSitePlus
S182EDSSWsSLDARPhosphoSitePlus
T272ITPPTtPQLRRPhosphoSitePlus; phosphoELM
T271FITPPtTPQLRPhosphoSitePlus
T597RKASQtSVYLQPkinasePhosphoSitePlus
S332DLSHGsPQMVRPhosphoSitePlus; phosphoELM
S476TPPNPsPGQRDPkinasePhosphoSitePlus

Dephosphorylation site
KSR1_HUMAN do not have dephosphorylation site.

Mutation site
KSR1_HUMAN do not have mutation site.

Differential expressed protein
KSR1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
KSR1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBB3_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG10_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG8_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBB2_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG2_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG3_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG11_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBB5_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG5_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBB1_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG12_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG13_HUMANKSR1_HUMANGprotein -> effectorgpDB
GBG1_HUMANKSR1_HUMANGprotein -> effectorgpDB
MARK3_HUMANKSR1_HUMANkinase -> substrateRegPhos
KSR1_HUMANRAF1_HUMANkinase -> substrateRegPhos
MK01_HUMANKSR1_HUMANkinase -> substrateHPRD
ZAGL2_HUMANKSR1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05152Tuberculosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005789endoplasmic reticulum membraneIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0035556intracellular signal transductionIEAbiological_process
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0005078MAP-kinase scaffold activityIEAmolecular_function
GO:0043410positive regulation of MAPK cascadeIEAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0006468protein phosphorylationNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0007265Ras protein signal transductionNASbiological_process
GO:0005622intracellularNAScellular_component
GO:0046872metal ion bindingIEAmolecular_function


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