| UniProt/SwissProt ID: | KSR1_HUMAN |
| Description: | kinase suppressor of ras 1 [Source:HGNC Symbol;Acc:6465] |
| Location: | chr17 q11.1 |
| Node attribute: | kinase; effector; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T423 | EPHFGtLPKAL | Pkinase | PhosphoSitePlus |
| S312 | SKSHEsQLGNR | PhosphoSitePlus | |
| Y721 | IKGMGyLHAKG | PhosphoSitePlus | |
| S291 | TPPPPsRKVFQ | PhosphoSitePlus | |
| S265 | PRALHsFITPP | PhosphoSitePlus | |
| S886 | LNRRLsHPGHF | PhosphoSitePlus | |
| T402 | TRLRRtESVPS | phosphoELM | |
| S227 | GPRSIsVSALP | PhosphoSitePlus | |
| S595 | ISRKAsQTSVY | Pkinase | PhosphoSitePlus |
| S236 | LPASDsPTPSF | PhosphoSitePlus | |
| Y160 | CGRLQyALTCL | PhosphoSitePlus | |
| T248 | EGLSDtCIPLH | PhosphoSitePlus | |
| S567 | PEAGKsEAEDD | phosphoELM | |
| T471 | PSSATtPPNPS | Pkinase | PhosphoSitePlus |
| S329 | MRFDLsHGSPQ | PhosphoSitePlus | |
| S307 | PTLTRsKSHES | PhosphoSitePlus | |
| T238 | ASDSPtPSFSE | PhosphoSitePlus | |
| S404 | LRRTEsVPSDI | Pkinase | PhosphoSitePlus |
| S404 | LRRTEsVPSDI | phosphoELM | |
| S404 | LRRTEsVPSDI | MARK3 | RegPhos |
| S255 | IPLHAsGRLTP | PhosphoSitePlus | |
| T268 | LHSFItPPTTP | PhosphoSitePlus; phosphoELM; SysPTM | |
| S567 | PEAGKsEAEDD | Pkinase | PhosphoSitePlus |
| S309 | LTRSKsHESQL | PhosphoSitePlus; phosphoELM; RegPhos; SysPTM | |
| T402 | TRLRRtESVPS | Pkinase | PhosphoSitePlus |
| T286 | LKPPRtPPPPS | PhosphoSitePlus | |
| S182 | EDSSWsSLDAR | PhosphoSitePlus | |
| T272 | ITPPTtPQLRR | PhosphoSitePlus; phosphoELM | |
| T271 | FITPPtTPQLR | PhosphoSitePlus | |
| T597 | RKASQtSVYLQ | Pkinase | PhosphoSitePlus |
| S332 | DLSHGsPQMVR | PhosphoSitePlus; phosphoELM | |
| S476 | TPPNPsPGQRD | Pkinase | PhosphoSitePlus |
| Dephosphorylation site |
| KSR1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| KSR1_HUMAN do not have mutation site. |
| Differential expressed protein |
| KSR1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KSR1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GBB3_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG10_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG8_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBB2_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG2_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG3_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG11_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBB5_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG5_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBB1_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG12_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG13_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| GBG1_HUMAN | KSR1_HUMAN | Gprotein -> effector | gpDB |
| MARK3_HUMAN | KSR1_HUMAN | kinase -> substrate | RegPhos |
| KSR1_HUMAN | RAF1_HUMAN | kinase -> substrate | RegPhos |
| MK01_HUMAN | KSR1_HUMAN | kinase -> substrate | HPRD |
| ZAGL2_HUMAN | KSR1_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05152 | Tuberculosis |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005789 | endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0035556 | intracellular signal transduction | IEA | biological_process |
| GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005078 | MAP-kinase scaffold activity | IEA | molecular_function |
| GO:0043410 | positive regulation of MAPK cascade | IEA | biological_process |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | NAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0007265 | Ras protein signal transduction | NAS | biological_process |
| GO:0005622 | intracellular | NAS | cellular_component |
| GO:0046872 | metal ion binding | IEA | molecular_function |