Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ETS2_HUMAN
Description:v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) [Source:HGNC Symbol;Acc:3489]
Location:chr21 q22.2
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S321DDCSQsLCLNKPhosphoSitePlus
T72ELPLLtPCSKAPhosphoSitePlus; HPRD; phosphoELM
S295DSLLQsWNSQSPhosphoSitePlus; HPRD; SysPTM
T226MCPAStPSVLSPhosphoSitePlus
S246KSRLSsVSVTYPhosphoSitePlus
S228PASTPsVLSSEPhosphoSitePlus
S313VPSFEsFEDDCPhosphoSitePlus
S319FEDDCsQSLCLPhosphoSitePlus
S310VQRVPsFESFEPhosphoSitePlus

Dephosphorylation site
ETS2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000353344G216SCOSMICBreast Cancer20668451
ENSP00000353344G356CCOSMICOvarian Cancer21720365
ENSP00000353344T72ACOSMICLung Cancer20016488
ENSP00000354194P362SCOSMICSkin Cancer21984974
ENSP00000353344W117LCOSMICHead and Neck Cancer21984974
ENSP00000354194G216SCOSMICBreast Cancer20668451
ENSP00000354194Q137EBIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000354194W117LCOSMICHead and Neck Cancer21984974
ENSP00000354194G356CCOSMICOvarian Cancer21720365
ENSP00000354194T72ACOSMICLung Cancer20016488
ENSP00000353344P362SCOSMICSkin Cancer21984974

Differential expressed protein
ETS2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ETS2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ETS2_HUMANTRBC1_HUMANTF -> target geneTRANSFAC
ETS2_HUMANIL12B_HUMANTF -> target geneTRANSFAC
ETS2_HUMANFOSL1_HUMANTF -> target geneTRANSFAC
ETS2_HUMANCDK1_HUMANTF -> target geneTRANSFAC
ETS2_HUMANPSN1_HUMANTF -> target geneTRANSFAC
ETS2_HUMANSURF1_HUMANTF -> target geneTRANSFAC
ETS2_HUMANMGAT2_HUMANTF -> target geneTRANSFAC
ETS2_HUMANCCND1_HUMANTF -> target geneTRANSFAC
ETS2_HUMANUROK_HUMANTF -> target geneTRANSFAC
ETS2_HUMANKIT_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
ETS2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003677DNA bindingTASmolecular_function
GO:0000977RNA polymerase II regulatory region sequence-speciIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0035259glucocorticoid receptor bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0001501skeletal system developmentTASbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process


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