| UniProt/SwissProt ID: | CORT_HUMAN |
| Description: | cortistatin [Source:HGNC Symbol;Acc:2257] |
| Location: | chr1 p36.22 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y14 | RLGLKyPPSSK | HPRD | |
| S32 | PTGRDsEHMQE | PhosphoSitePlus | |
| Dephosphorylation site |
| CORT_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000366248 | *106C | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| CORT_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CORT_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CORT_HUMAN | SSR3_HUMAN | ligand -> receptor | HPMR |
| CORT_HUMAN | GHSR_HUMAN | ligand -> receptor | HPMR |
| CORT_HUMAN | MRGX2_HUMAN | ligand -> receptor | HPMR |
| CORT_HUMAN | SSR1_HUMAN | ligand -> receptor | HPMR |
| CORT_HUMAN | SSR2_HUMAN | ligand -> receptor | HPMR |
| CORT_HUMAN | SSR4_HUMAN | ligand -> receptor | HPMR |
| CORT_HUMAN | SSR5_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| CORT_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007268 | synaptic transmission | NAS | biological_process |
| GO:0005615 | extracellular space | NAS | cellular_component |
| GO:0005179 | hormone activity | IEA | molecular_function |
| GO:0005576 | extracellular region | IEA | cellular_component |
| GO:0007193 | adenylate cyclase-inhibiting G-protein coupled rec | IDA | biological_process |
| GO:0005184 | neuropeptide hormone activity | IDA | molecular_function |
| GO:0001664 | G-protein coupled receptor binding | IPI | molecular_function |