Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CDK16_HUMAN
Description:cyclin-dependent kinase 16 [Source:HGNC Symbol;Acc:8749]
Location:chrX p11.23
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S319PTKTYsNEVVTphosphoELM
S78DLKMGsDGESDPhosphoSitePlus; HPRD
S42GGGGGsDPGEAPhosphoSitePlus; HPRD
S12IKRQLsMTLRGPhosphoSitePlus
S110PPRKIsTEDINPKA_groupphosphoELM
S110PPRKIsTEDINPRKACAHPRD
S119INKRLsLPADIPRKACAHPRD
T88DQASAtSSDEVPhosphoSitePlus; HPRD
S12IKRQLsMTLRGPRKACAHPRD
S95SDEVQsPVRVRPhosphoSitePlus
S119INKRLsLPADIPhosphoSitePlus; HPRD; phosphoELM
S36IGLDEsGGGGGPhosphoSitePlus; HPRD
S480SLRSSsMPDSGPhosphoSitePlus; HPRD; phosphoELM
S155RRVSLsEIGFGPhosphoSitePlus; HPRD; phosphoELM
S153RLRRVsLSEIGPKA_groupphosphoELM
S89QASATsSDEVQPhosphoSitePlus; HPRD
T135YLEKLtLNSPIPhosphoSitePlus; HPRD
T175KLGEGtYATVYPkinasePhosphoSitePlus
S86ESDQAsATSSDPhosphoSitePlus; HPRD
S138KLTLNsPIFDKCDK16HPRD
Y180TYATVyKGKSKHPRD
Y176LGEGTyATVYKPkinasePhosphoSitePlus
S12IKRQLsMTLRGPKA_groupphosphoELM
S65RGPLSsAPEIVPhosphoSitePlus; HPRD
S95SDEVQsPVRVRCDK5HPRD
S153RLRRVsLSEIGPRKACAHPRD
Y176LGEGTyATVYKHPRD; phosphoELM
T178EGTYAtVYKGKHPRD
S479ASLRSsSMPDSPhosphoSitePlus
T14RQLSMtLRGGRPhosphoSitePlus
Y180TYATVyKGKSKPkinasePhosphoSitePlus
S95SDEVQsPVRVRCDK_groupphosphoELM
T178EGTYAtVYKGKPkinasePhosphoSitePlus
S153RLRRVsLSEIGPhosphoSitePlus; HPRD; phosphoELM
S64ARGPLsSAPEIPhosphoSitePlus; HPRD
S110PPRKIsTEDINPhosphoSitePlus
S138KLTLNsPIFDKPhosphoSitePlus; phosphoELM
S82GSDGEsDQASAPhosphoSitePlus; HPRD
T111PRKIStEDINKPhosphoSitePlus
S119INKRLsLPADIPKA_groupphosphoELM
S90ASATSsDEVQSHPRD
T175KLGEGtYATVYHPRD

Dephosphorylation site
CDK16_HUMAN do not have dephosphorylation site.

Mutation site
CDK16_HUMAN do not have mutation site.

Differential expressed protein
CDK16_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CDK16_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK16_HUMANAVR2B_HUMANkinase -> substrateRobert H Newman (2013)
CDK16_HUMANCDK16_HUMANkinase -> substrateHPRD
KPCA_HUMANCDK16_HUMANkinase -> substrateHPRD
CDK16_HUMANCRK_HUMANkinase -> substrateRobert H Newman (2013)
ARAF_HUMANCDK16_HUMANkinase -> substrateRobert H Newman (2013)
KKCC2_HUMANCDK16_HUMANkinase -> substrateRobert H Newman (2013)
CDK5_HUMANCDK16_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANCDK16_HUMANkinase -> substrateRegPhos
CDK16_HUMANFAK2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CDK16_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031234extrinsic to internal side of plasma membraneIDAcellular_component
GO:0043005neuron projectionIEAcellular_component
GO:0030252growth hormone secretionIEAbiological_process
GO:0030133transport vesicleIEAcellular_component
GO:0008021synaptic vesicleIEAcellular_component
GO:0061178regulation of insulin secretion involved in cellulIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0030054cell junctionIEAcellular_component
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0006887exocytosisIEAbiological_process
GO:0007283spermatogenesisIEAbiological_process
GO:0006468protein phosphorylationTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0004693cyclin-dependent protein kinase activityIEAmolecular_function
GO:0031175neuron projection developmentIEAbiological_process
GO:0004672protein kinase activityIEAmolecular_function