Phosphorylation

Protein information

Protein summary

Phosphorylation site

Dephosphorylation site

Mutation site

Differential expressed protein

Hyperphosphorylation site

Direct interaction pair

Function Annotation

Protein Summary

UniProt/SwissProt ID:	SPI1_HUMAN
Description:	spleen focus forming virus (SFFV) proviral integration oncogene spi1 [Source:HGNC Symbol;Acc:11241]
Location:	chr11 p11.2
Node attribute:	TF

Phosphorylation site

Position	PhosphoPeptide	Catalytic kinase	Source
S17	LVPPPsEDLVP		PhosphoSitePlus

Dephosphorylation site

SPI1_HUMAN do not have dephosphorylation site.

Mutation site

SPI1_HUMAN do not have mutation site.

Differential expressed protein

SPI1_HUMAN is not differential expressed protein.

Hyperphosphorylation site

SPI1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair

Source	Target	Relationship	Resource
SPI1_HUMAN	ISG15_HUMAN	TF -> target gene	TRANSFAC
SPI1_HUMAN	NCF4_HUMAN	TF -> target gene	TRANSFAC
SPI1_HUMAN	IL12B_HUMAN	TF -> target gene	TRANSFAC
SPI1_HUMAN	IL1B_HUMAN	TF -> target gene	TRANSFAC
SPI1_HUMAN	ITA2B_HUMAN	TF -> target gene	TRANSFAC
SPI1_HUMAN	ITAM_HUMAN	TF -> target gene	TRANSFAC

Function Annotation

KEGG Pathway

SPI1_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0030225	macrophage differentiation	IEA	biological_process
GO:0043565	sequence-specific DNA binding	IEA	molecular_function
GO:0035019	somatic stem cell maintenance	IEA	biological_process
GO:0001085	RNA polymerase II transcription factor binding	IEA	molecular_function
GO:0001944	vasculature development	IEA	biological_process
GO:0000980	RNA polymerase II distal enhancer sequence-specifi	ISS	molecular_function
GO:0005515	protein binding	IPI	molecular_function
GO:0030851	granulocyte differentiation	IEA	biological_process
GO:0003700	sequence-specific DNA binding transcription factor	IDA	molecular_function
GO:0045814	negative regulation of gene expression, epigenetic	IDA	biological_process
GO:0045892	negative regulation of transcription, DNA-dependen	IDA	biological_process
GO:0001047	core promoter binding	IDA	molecular_function
GO:0030098	lymphocyte differentiation	IEA	biological_process
GO:0030218	erythrocyte differentiation	IEA	biological_process
GO:0060033	anatomical structure regression	IEA	biological_process
GO:0000790	nuclear chromatin	IDA	cellular_component
GO:0003705	RNA polymerase II distal enhancer sequence-specifi	IEA	molecular_function
GO:0006357	regulation of transcription from RNA polymerase II	IEA	biological_process
GO:0003700	sequence-specific DNA binding transcription factor	IEA	molecular_function
GO:0045944	positive regulation of transcription from RNA poly	IEA	biological_process
GO:0005515	protein binding	IEA	molecular_function
GO:0043966	histone H3 acetylation	IMP	biological_process
GO:0002320	lymphoid progenitor cell differentiation	IEA	biological_process
GO:0044027	hypermethylation of CpG island	IDA	biological_process
GO:0003705	RNA polymerase II distal enhancer sequence-specifi	ISS	molecular_function
GO:0003723	RNA binding	IEA	molecular_function
GO:0045893	positive regulation of transcription, DNA-dependen	IDA	biological_process
GO:0045893	positive regulation of transcription, DNA-dependen	IEA	biological_process
GO:0000122	negative regulation of transcription from RNA poly	TAS	biological_process
GO:0006355	regulation of transcription, DNA-dependent	IEA	biological_process
GO:0045646	regulation of erythrocyte differentiation	IMP	biological_process
GO:0051525	NFAT protein binding	IEA	molecular_function
GO:0000980	RNA polymerase II distal enhancer sequence-specifi	IEA	molecular_function
GO:0005634	nucleus	IEA	cellular_component
GO:0090241	negative regulation of histone H4 acetylation	IMP	biological_process
GO:0006917	induction of apoptosis	IEA	biological_process
GO:0000790	nuclear chromatin	IEA	cellular_component
GO:0001085	RNA polymerase II transcription factor binding	ISS	molecular_function
GO:0003677	DNA binding	IEA	molecular_function
GO:0045944	positive regulation of transcription from RNA poly	ISS	biological_process
GO:0002573	myeloid leukocyte differentiation	IEA	biological_process
GO:0001205	RNA polymerase II distal enhancer sequence-specifi	IEA	molecular_function
GO:0045347	negative regulation of MHC class II biosynthetic p	IEA	biological_process
GO:0043011	myeloid dendritic cell differentiation	IEA	biological_process
GO:0051525	NFAT protein binding	ISS	molecular_function

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network