Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SLTM_HUMAN
Description:SAFB-like, transcription modulator [Source:HGNC Symbol;Acc:20709]
Location:chr15 q22.1
Node attribute:substrate; kinase; receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S515SEKKEsKDTKKPhosphoSitePlus; HPRD
T938DRGVItDRGGGPhosphoSitePlus
S553RISSKsPGHMVPhosphoSitePlus; HPRD
S371KDDKGsTSSTSPhosphoSitePlus
T399SAKVVtNARSPHPRD
S1002HSSNAsPINRIPhosphoSitePlus; HPRD
T417SAKVVtNARSPHPRD
S891SGREVsGHSVRHPRD
S532EKKRIsSKSPGHPRD
T254KNVKItDSEASHPRD
S944DRGGGsQHYPEPhosphoSitePlus
S482SSSRSsGDKKNPhosphoSitePlus
T5_MAAAtGAVAAPhosphoSitePlus
S583KIHGRsKEKERPhosphoSitePlus; HPRD
S1021PRGSGsGFKPFPhosphoSitePlus; HPRD
T418TMSSStEVSRCHPRD
S535RISSKsPGHMVHPRD
T436TMSSStEVSRCRRM_1PhosphoSitePlus
S1014QISGNsMPRGSPhosphoSitePlus; HPRD
T733KLSLDtDARFGHPRD
S477ENDEKsSSRSSPhosphoSitePlus
S551KKRISsKSPGHPhosphoSitePlus; HPRD
S533KKRISsKSPGHHPRD
S14AASAAsGQAEGPhosphoSitePlus; HPRD
S525ESIKKsEEKKRHPRD
S725QEKRNsLKRPRPhosphoSitePlus
T72ELTVStDTPNKPhosphoSitePlus
S550EKKRIsSKSPGPhosphoSitePlus; HPRD
T436TMSSStEVSRCHPRD
T74TVSTDtPNKKPPhosphoSitePlus; HPRD
S1003PRGSGsGFKPFHPRD
S354GQAKSsSKESKPhosphoSitePlus
S539GQTSEsIKKSEPhosphoSitePlus
T80PNKKPtKGKGKPhosphoSitePlus
S759RFGHGsDYSRQPhosphoSitePlus
S97LSGDAsVEDDAPhosphoSitePlus; HPRD
T977GAGMItQHSSNHPRD
S565KIHGRsKEKERHPRD
S11GAVAAsAASGQHPRD
T751KLSLDtDARFGPhosphoSitePlus; HPRD
T995GAGMItQHSSNPhosphoSitePlus; HPRD
S1001SMPRGsGSGFKHPRD
S1019SMPRGsGSGFKPhosphoSitePlus; HPRD
T272KNVKItDSEASHPRD
S421VTNARsPGAKCHPRD
S170KEDIEsQEIEAPhosphoSitePlus
S909SGREVsGHSVRPhosphoSitePlus; HPRD
S93EADELsGDASVPhosphoSitePlus; HPRD
S144SKELLsAEENKPhosphoSitePlus; HPRD
S344KKGPSsTGASGPhosphoSitePlus
S980MITQHsSNASPHPRD
Y761GHGSDySRQQNPhosphoSitePlus
S343LKKGPsSTGASPhosphoSitePlus
S271DAIAQsPEKESHPRD
T69DNIELtVSTDTHPRD
S497SEKKEsKDTKKHPRD
Y297KESKDyEMNANHPRD
S730ENKKLsLDTDAHPRD
S294SPEKEsKDYEMHPRD
S797RREDPsFERYPHPRD
S433GIVTMsSSTEVHPRD
S996QISGNsMPRGSHPRD
S998MITQHsSNASPHPRD
S415GIVTMsSSTEVHPRD
S289DAIAQsPEKESPhosphoSitePlus; HPRD; SysPTM
Y279KESKDyEMNANHPRD
S543ESIKKsEEKKRPhosphoSitePlus; HPRD
S244EDDNIsVTIQAHPRD
S572EKERAsLDKKRHPRD
S984HSSNAsPINRIHPRD
S815RREDPsFERYPHPRD
S782RFVGQsEGKKAHPRD
S276SPEKEsKDYEMHPRD
T536GASGQtSESIKPhosphoSitePlus
S590EKERAsLDKKRPhosphoSitePlus; HPRD
S226EDDNIsVTIQAHPRD
S403VTNARsPGAKCHPRD
S421VTNARsPGAKCRRM_1PhosphoSitePlus
S748ENKKLsLDTDAPhosphoSitePlus; HPRD
S800RFVGQsEGKKAPhosphoSitePlus; HPRD
T345KGPSStGASGQPhosphoSitePlus

Dephosphorylation site
SLTM_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000369887A638TBIOMARTBreast Cancer21930507, 21930502
ENSP00000369887S325CCOSMICHead and Neck Cancer21798893
ENSP00000369887M299ICOSMICSkin Cancer21984974

Differential expressed protein
SLTM_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SLTM_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HGF_HUMANSLTM_HUMANligand -> receptorHPMR
SLTM_HUMANUB2L3_HUMANkinase -> substrateRobert H Newman (2013)
SLTM_HUMANMTA1_HUMANkinase -> substrateRobert H Newman (2013)
SLTM_HUMANSLTM_HUMANkinase -> substrateHPRD
SLTM_HUMANSRC8_HUMANkinase -> substrateRobert H Newman (2013)
SLTM_HUMANKPCA_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANSLTM_HUMANkinase -> substrateRegPhos
SLTM_HUMANITB4_HUMANkinase -> substrateNetPath
SLTM_HUMANNFAC4_HUMANkinase -> substrateRobert H Newman (2013)
SLTM_HUMANSPSB1_HUMANkinase -> substrateRegPhos
SLTM_HUMANABI2_HUMANkinase -> substrateRobert H Newman (2013)
KPCD_HUMANSLTM_HUMANkinase -> substrateRobert H Newman (2013)
SLTM_HUMANGAB1_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
PTPRJ_HUMANSLTM_HUMANphosphatase -> substrateHPRD
HGF_HUMANSLTM_HUMANotherKEGG

Function Annotation
KEGG Pathway
SLTM_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0006915apoptotic processIEAbiological_process
GO:0000166nucleotide bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIDAcellular_component


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