| UniProt/SwissProt ID: | SLTM_HUMAN |
| Description: | SAFB-like, transcription modulator [Source:HGNC Symbol;Acc:20709] |
| Location: | chr15 q22.1 |
| Node attribute: | substrate; kinase; receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S515 | SEKKEsKDTKK | PhosphoSitePlus; HPRD | |
| T938 | DRGVItDRGGG | PhosphoSitePlus | |
| S553 | RISSKsPGHMV | PhosphoSitePlus; HPRD | |
| S371 | KDDKGsTSSTS | PhosphoSitePlus | |
| T399 | SAKVVtNARSP | HPRD | |
| S1002 | HSSNAsPINRI | PhosphoSitePlus; HPRD | |
| T417 | SAKVVtNARSP | HPRD | |
| S891 | SGREVsGHSVR | HPRD | |
| S532 | EKKRIsSKSPG | HPRD | |
| T254 | KNVKItDSEAS | HPRD | |
| S944 | DRGGGsQHYPE | PhosphoSitePlus | |
| S482 | SSSRSsGDKKN | PhosphoSitePlus | |
| T5 | _MAAAtGAVAA | PhosphoSitePlus | |
| S583 | KIHGRsKEKER | PhosphoSitePlus; HPRD | |
| S1021 | PRGSGsGFKPF | PhosphoSitePlus; HPRD | |
| T418 | TMSSStEVSRC | HPRD | |
| S535 | RISSKsPGHMV | HPRD | |
| T436 | TMSSStEVSRC | RRM_1 | PhosphoSitePlus |
| S1014 | QISGNsMPRGS | PhosphoSitePlus; HPRD | |
| T733 | KLSLDtDARFG | HPRD | |
| S477 | ENDEKsSSRSS | PhosphoSitePlus | |
| S551 | KKRISsKSPGH | PhosphoSitePlus; HPRD | |
| S533 | KKRISsKSPGH | HPRD | |
| S14 | AASAAsGQAEG | PhosphoSitePlus; HPRD | |
| S525 | ESIKKsEEKKR | HPRD | |
| S725 | QEKRNsLKRPR | PhosphoSitePlus | |
| T72 | ELTVStDTPNK | PhosphoSitePlus | |
| S550 | EKKRIsSKSPG | PhosphoSitePlus; HPRD | |
| T436 | TMSSStEVSRC | HPRD | |
| T74 | TVSTDtPNKKP | PhosphoSitePlus; HPRD | |
| S1003 | PRGSGsGFKPF | HPRD | |
| S354 | GQAKSsSKESK | PhosphoSitePlus | |
| S539 | GQTSEsIKKSE | PhosphoSitePlus | |
| T80 | PNKKPtKGKGK | PhosphoSitePlus | |
| S759 | RFGHGsDYSRQ | PhosphoSitePlus | |
| S97 | LSGDAsVEDDA | PhosphoSitePlus; HPRD | |
| T977 | GAGMItQHSSN | HPRD | |
| S565 | KIHGRsKEKER | HPRD | |
| S11 | GAVAAsAASGQ | HPRD | |
| T751 | KLSLDtDARFG | PhosphoSitePlus; HPRD | |
| T995 | GAGMItQHSSN | PhosphoSitePlus; HPRD | |
| S1001 | SMPRGsGSGFK | HPRD | |
| S1019 | SMPRGsGSGFK | PhosphoSitePlus; HPRD | |
| T272 | KNVKItDSEAS | HPRD | |
| S421 | VTNARsPGAKC | HPRD | |
| S170 | KEDIEsQEIEA | PhosphoSitePlus | |
| S909 | SGREVsGHSVR | PhosphoSitePlus; HPRD | |
| S93 | EADELsGDASV | PhosphoSitePlus; HPRD | |
| S144 | SKELLsAEENK | PhosphoSitePlus; HPRD | |
| S344 | KKGPSsTGASG | PhosphoSitePlus | |
| S980 | MITQHsSNASP | HPRD | |
| Y761 | GHGSDySRQQN | PhosphoSitePlus | |
| S343 | LKKGPsSTGAS | PhosphoSitePlus | |
| S271 | DAIAQsPEKES | HPRD | |
| T69 | DNIELtVSTDT | HPRD | |
| S497 | SEKKEsKDTKK | HPRD | |
| Y297 | KESKDyEMNAN | HPRD | |
| S730 | ENKKLsLDTDA | HPRD | |
| S294 | SPEKEsKDYEM | HPRD | |
| S797 | RREDPsFERYP | HPRD | |
| S433 | GIVTMsSSTEV | HPRD | |
| S996 | QISGNsMPRGS | HPRD | |
| S998 | MITQHsSNASP | HPRD | |
| S415 | GIVTMsSSTEV | HPRD | |
| S289 | DAIAQsPEKES | PhosphoSitePlus; HPRD; SysPTM | |
| Y279 | KESKDyEMNAN | HPRD | |
| S543 | ESIKKsEEKKR | PhosphoSitePlus; HPRD | |
| S244 | EDDNIsVTIQA | HPRD | |
| S572 | EKERAsLDKKR | HPRD | |
| S984 | HSSNAsPINRI | HPRD | |
| S815 | RREDPsFERYP | HPRD | |
| S782 | RFVGQsEGKKA | HPRD | |
| S276 | SPEKEsKDYEM | HPRD | |
| T536 | GASGQtSESIK | PhosphoSitePlus | |
| S590 | EKERAsLDKKR | PhosphoSitePlus; HPRD | |
| S226 | EDDNIsVTIQA | HPRD | |
| S403 | VTNARsPGAKC | HPRD | |
| S421 | VTNARsPGAKC | RRM_1 | PhosphoSitePlus |
| S748 | ENKKLsLDTDA | PhosphoSitePlus; HPRD | |
| S800 | RFVGQsEGKKA | PhosphoSitePlus; HPRD | |
| T345 | KGPSStGASGQ | PhosphoSitePlus | |
| Dephosphorylation site |
| SLTM_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000369887 | A638T | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000369887 | S325C | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000369887 | M299I | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| SLTM_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SLTM_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HGF_HUMAN | SLTM_HUMAN | ligand -> receptor | HPMR |
| SLTM_HUMAN | UB2L3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SLTM_HUMAN | MTA1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SLTM_HUMAN | SLTM_HUMAN | kinase -> substrate | HPRD |
| SLTM_HUMAN | SRC8_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SLTM_HUMAN | KPCA_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ZAGL2_HUMAN | SLTM_HUMAN | kinase -> substrate | RegPhos |
| SLTM_HUMAN | ITB4_HUMAN | kinase -> substrate | NetPath |
| SLTM_HUMAN | NFAC4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SLTM_HUMAN | SPSB1_HUMAN | kinase -> substrate | RegPhos |
| SLTM_HUMAN | ABI2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCD_HUMAN | SLTM_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SLTM_HUMAN | GAB1_HUMAN | kinase -> substrate | RegPhos; Robert H Newman (2013) |
| PTPRJ_HUMAN | SLTM_HUMAN | phosphatase -> substrate | HPRD |
| HGF_HUMAN | SLTM_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| SLTM_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0006915 | apoptotic process | IEA | biological_process |
| GO:0000166 | nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |