Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SAFB2_HUMAN
Description:scaffold attachment factor B2 [Source:HGNC Symbol;Acc:21605]
Location:chr19 p13.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S832SDKRLsEGRGLPhosphoSitePlus; HPRD; phosphoELM
S226GETCKsEPVKEPhosphoSitePlus; HPRD; phosphoELM
S330ELAEAsSEELAPhosphoSitePlus; HPRD; phosphoELM
S17GPGTAsLGPGVPhosphoSitePlus
Y825DGWGGyGSDKRPhosphoSitePlus
S194NTLETsSLNFKPhosphoSitePlus; HPRD
S287SSKADsLLAVVPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S195TLETSsLNFKVPhosphoSitePlus; HPRD; phosphoELM
S245FAQDTsSVGPDPhosphoSitePlus; HPRD; phosphoELM
S85ATSKKsAKRCVPhosphoSitePlus
Y776RDRGQyQDHAIPhosphoSitePlus
S591KTTSRsKERSSPhosphoSitePlus
S11PGSGDsGPGTAPhosphoSitePlus
T339LAEAPtEAPSPPhosphoSitePlus
S331LAEASsEELAEPhosphoSitePlus; HPRD; phosphoELM
Y741RRDDAyWPEGKPhosphoSitePlus
S444VTNARsPGARCRRM_1PhosphoSitePlus
T471SHLHRtELHGRRRM_1PhosphoSitePlus
T244PFAQDtSSVGPPhosphoSitePlus; HPRD; phosphoELM
S613KRDILsFDKIKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S349PEARDsKEDGRPhosphoSitePlus; HPRD; phosphoELM
S31GTRRLsELRVISAPPhosphoSitePlus
S109GLEDDsRDGQEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S233PVKEEsSELEQPhosphoSitePlus; HPRD; phosphoELM
T440GAKVVtNARSPRRM_1PhosphoSitePlus
S479HGRMIsVEKAKRRM_1PhosphoSitePlus
T4PGSGHPRD
S54TGGNKsVLMERHPRD
S444VTNARsPGARCHPRD
S246AQDTSsVGPDRPhosphoSitePlus; HPRD; phosphoELM
S8ETLPGsGDSGPHPRD
S506KKEKLsSVDRHHPRD
S234VKEESsELEQPPhosphoSitePlus; HPRD; phosphoELM
Y754AMEDRyRADFPPhosphoSitePlus
T201LNFKVtPDIEEPhosphoSitePlus; HPRD
S513VDRHHsVEIKIPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T4__MAEtLPGSGPhosphoSitePlus
S207PDIEEsLLEPEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T588ISVKTtSRSKEPhosphoSitePlus
S343PTEAPsPEARDPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S827WGGYGsDKRLSPhosphoSitePlus
S31GTRRLsELRVIHPRD

Dephosphorylation site
SAFB2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000252542T561ICOSMICHead and Neck Cancer21798893
ENSP00000252542S132NCOSMICOvarian Cancer21720365
ENSP00000252542H915NCOSMICSkin Cancer21984974

Differential expressed protein
SAFB2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SAFB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLK2_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
NEK2_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
ARAF_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
KS6A2_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
MP2K7_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
KS6B1_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
KS6A4_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
TGFR2_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
DYRK4_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
STK11_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
MAPK5_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANSAFB2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SAFB2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0000166nucleotide bindingIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0003677DNA bindingIEAmolecular_function


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