| UniProt/SwissProt ID: | PTN7_HUMAN |
| Description: | protein tyrosine phosphatase, non-receptor type 7 [Source:HGNC Symbol;Acc:9659] |
| Location: | chr1 q32.1 |
| Node attribute: | substrate; phosphotase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S110 | PSNFVsPEDLD | PhosphoSitePlus | |
| S93 | QRQPPsPKQLE | PhosphoSitePlus; phosphoELM; RegPhos | |
| Y154 | YINANyIRGYD | Y_phosphatase | PhosphoSitePlus |
| S63 | VEPICsVNTPR | PhosphoSitePlus | |
| T210 | VHYWPtEEETY | Y_phosphatase | PhosphoSitePlus |
| S44 | QERRGsNVALM | PhosphoSitePlus; phosphoELM; RegPhos; SysPTM | |
| S132 | QRQPPsPKQLE | MAPK14 | HPRD |
| S143 | LGRAQsQEDGD | Y_phosphatase | PhosphoSitePlus |
| T66 | ICSVNtPREVT | p38a | RegPhos; SysPTM |
| S106 | FLKIPsNFVSP | PhosphoSitePlus | |
| S132 | QRQPPsPKQLE | MAPK3 | HPRD |
| S177 | MPNTVsDFWEM | Y_phosphatase | PhosphoSitePlus |
| Y215 | TEEETyGPFQI | Y_phosphatase | PhosphoSitePlus |
| Y149 | QEDGDyINANY | Y_phosphatase | PhosphoSitePlus |
| S93 | QRQPPsPKQLE | p38a | RegPhos |
| T66 | ICSVNtPREVT | PhosphoSitePlus; phosphoELM; RegPhos; SysPTM | |
| T66 | ICSVNtPREVT | Erk2 | RegPhos; SysPTM |
| T66 | ICSVNtPREVT | Erk1 | RegPhos; SysPTM |
| S54 | MLDVRsLGAVE | PhosphoSitePlus | |
| S132 | QRQPPsPKQLE | MAPK1 | HPRD |
| T105 | ICSVNtPREVT | MAPK1 | HPRD |
| T105 | ICSVNtPREVT | MAPK14 | HPRD |
| S83 | QERRGsNVALM | PRKACA | HPRD |
| S44 | QERRGsNVALM | PKA_group | phosphoELM; RegPhos; SysPTM |
| S246 | QEERRsVKHIL | Y_phosphatase | PhosphoSitePlus |
| S93 | QRQPPsPKQLE | Erk2 | RegPhos |
| S93 | QRQPPsPKQLE | Erk1 | RegPhos |
| T105 | ICSVNtPREVT | MAPK3 | HPRD |
| S134 | LPNPQsRVCLG | Y_phosphatase | PhosphoSitePlus |
| S44 | QERRGsNVALM | PKACa | RegPhos; SysPTM |
| T214 | PTEEEtYGPFQ | Y_phosphatase | PhosphoSitePlus |
| S359 | LPEEPsP____ | PhosphoSitePlus | |
| Dephosphorylation site |
| PTN7_HUMAN do not have dephosphorylation site. |
| Mutation site |
| PTN7_HUMAN do not have mutation site. |
| Differential expressed protein |
| PTN7_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PTN7_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK03_HUMAN | PTN7_HUMAN | kinase -> substrate | HPRD |
| KPCA_HUMAN | PTN7_HUMAN | kinase -> substrate | HPRD |
| ZAGL2_HUMAN | PTN7_HUMAN | kinase -> substrate | RegPhos |
| MK01_HUMAN | PTN7_HUMAN | kinase -> substrate | HPRD |
| MK14_HUMAN | PTN7_HUMAN | kinase -> substrate | HPRD |
| PTN7_HUMAN | MK14_HUMAN | phosphatase -> substrate | KEGG |
| PTN7_HUMAN | MK08_HUMAN | phosphatase -> substrate | KEGG |
| PTN7_HUMAN | MK01_HUMAN | phosphatase -> substrate | HPRD; KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04010 | MAPK signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006470 | protein dephosphorylation | TAS | biological_process |
| GO:0035335 | peptidyl-tyrosine dephosphorylation | TAS | biological_process |
| GO:0009898 | internal side of plasma membrane | IDA | cellular_component |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0004725 | protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0016311 | dephosphorylation | IEA | biological_process |
| GO:0016791 | phosphatase activity | IEA | molecular_function |
| GO:0005829 | cytosol | IEA | cellular_component |