Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTAFR_HUMAN
Description:platelet-activating factor receptor [Source:HGNC Symbol;Acc:9582]
Location:chr1 p35.3
Node attribute:GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S339QIPGNsLKN__PhosphoSitePlus

Dephosphorylation site
PTAFR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000301974H4YBIOMARTBreast Cancer21930507, 21930502
ENSP00000362965H4YBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
PTAFR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTAFR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTAFR_HUMANGNA11_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNAI1_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNAO_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNAI2_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNAQ_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04020Calcium signaling pathway
hsa05150Staphylococcus aureus infection
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0060333interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0016020membraneIDAcellular_component
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0001875lipopolysaccharide receptor activityIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0031663lipopolysaccharide-mediated signaling pathwayIEAbiological_process
GO:0016021integral to membraneNAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayIMPbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0048015phosphatidylinositol-mediated signalingIDAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0032959inositol trisphosphate biosynthetic processIEAbiological_process
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0006935chemotaxisIEAbiological_process
GO:0001530lipopolysaccharide bindingIEAmolecular_function
GO:0004992platelet activating factor receptor activityIDAmolecular_function
GO:0006955immune responseTASbiological_process
GO:0005543phospholipid bindingIDAmolecular_function
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0001816cytokine productionIEAbiological_process


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