Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PAR3_HUMAN
Description:coagulation factor II (thrombin) receptor-like 2 [Source:HGNC Symbol;Acc:3539]
Location:chr5 q13.3
Node attribute:receptor; GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y224ATVFLyMLPFF7tm_1; TMPhosphoSitePlus

Dephosphorylation site
PAR3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000296641L141FCOSMICMelanoma20016485
ENSP00000296641F6VCOSMICOvarian Cancer21720365

Differential expressed protein
PAR3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PAR3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
THRB_HUMANPAR3_HUMANligand -> receptorHPMR
PAR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNAI1_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNA11_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNAI2_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNAO_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0015057thrombin receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0007596blood coagulationTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0016324apical plasma membraneIEAcellular_component
GO:0009611response to woundingTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0004435phosphatidylinositol phospholipase C activityTASmolecular_function
GO:0030168platelet activationTASbiological_process


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